ZIM2 and TCHP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZIM2	TCHP
Description		zinc finger imprinted 2	trichoplein keratin filament binding
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus	Cytoplasm Mitochondrion Centrosome Cytosol Plasma Membrane Desmosome Keratin Filament Apical Cortex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II	Apoptotic Process Cell Projection Organization Negative Regulation Of Cell Growth Negative Regulation Of Cilium Assembly
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Triglyceride levels ( 32203549)	Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolite levels (MHPG) ( 23319000) Myocardial infarction ( 30226566) Platelet count ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		31 interacting genes: AQP1 BAG4 CATSPER1 CCDC120 EPM2AIP1 FAM161A GLYCTK HOXA1 IL16 KRTAP10-6 KRTAP10-7 KRTAP12-2 KRTAP2-3 KRTAP2-4 KRTAP3-2 LIMS1 MDFI MID2 MKRN3 PATZ1 PHF1 POLR1C POU6F2 SCNM1 TCHP TEKT4 TNS2 TTC23 USP2 ZNF383 ZNF587	53 interacting genes: ATPAF2 BCAS2 C21orf91 CBY2 CCDC125 CCDC13 CCDC172 CCDC85B CDR2 CDR2L DMAP1 DYDC1 EIF4ENIF1 HOOK2 ID2 IFFO1 IKZF3 KCTD17 KIAA0753 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT32 KRT34 KRT35 KRT40 KRT5 KRT6A KRT75 KRT8 MIIP MIPOL1 MKRN3 MTUS2 NAB2 NDOR1 NME7 NUP54 PRDM16 PSMB5 RABGEF1 RUSC1 TEX11 TRIM27 TRIM54 TSPAN15 USHBP1 VIM WWOX ZIM2
Entrez ID		23619	84260
HPRD ID		10321	14403
Ensembl ID		ENSG00000269699	ENSG00000139437
Uniprot IDs		A0A024R4S8 Q9NZV7	A0A024RBM9 Q9BT92
PDB IDs
Enriched GO Terms of Interacting Partners?
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