ZIM2 and LIMS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZIM2	LIMS1
Description		zinc finger imprinted 2	LIM zinc finger domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus	Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding	Protein Binding Zinc Ion Binding Protein Kinase Binding Protein-containing Complex Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II	Epithelial To Mesenchymal Transition Cell Aging Positive Regulation Of Gene Expression Positive Regulation Of Cell-substrate Adhesion Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of GTPase Activity Establishment Of Protein Localization Cell-cell Junction Organization Negative Regulation Of Transcription, DNA-templated Regulation Of Epithelial Cell Proliferation Positive Regulation Of Focal Adhesion Assembly Cellular Response To Transforming Growth Factor Beta Stimulus Cell-cell Adhesion Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways		Generic Transcription Pathway	Cell-extracellular matrix interactions Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Triglyceride levels ( 32203549)	Apolipoprotein B levels ( 32203549) Beard thickness ( 26926045) Birth weight ( 31043758) Excessive hairiness ( 29895819) Eyebrow thickness ( 26926045) Immature fraction of reticulocytes ( 32888494) LDL cholesterol ( 30275531) LDL cholesterol levels ( 32203549) Monobrow thickness ( 26926045) Scalp hair shape ( 26926045) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		31 interacting genes: AQP1 BAG4 CATSPER1 CCDC120 EPM2AIP1 FAM161A GLYCTK HOXA1 IL16 KRTAP10-6 KRTAP10-7 KRTAP12-2 KRTAP2-3 KRTAP2-4 KRTAP3-2 LIMS1 MDFI MID2 MKRN3 PATZ1 PHF1 POLR1C POU6F2 SCNM1 TCHP TEKT4 TNS2 TTC23 USP2 ZNF383 ZNF587	48 interacting genes: ADAMTS9 ATXN10 CATSPER1 CCN2 COL8A1 CSRP3 CWF19L2 DAPK1 EHMT2 FAM90A1 FERMT2 FERMT3 FMR1 GEM ILK INO80B IPO7 KAT8 KPRP LMO3 LPXN MBIP MYO15B NCK2 NEB OSR2 PARVA PEG3 PLCE1 RAD51D RBBP8 RSU1 SCNM1 SMURF1 TBC1D22B TCEA2 TGFBR1 TMSB4X TRIO TTN USP11 ZIM2 ZMYM4 ZNF160 ZNF410 ZNF417 ZNF564 ZNF587
Entrez ID		23619	3987
HPRD ID		10321	03978
Ensembl ID		ENSG00000269699	ENSG00000169756
Uniprot IDs		A0A024R4S8 Q9NZV7	P48059
PDB IDs			1G47 1NYP 1U5S 2COR 2D8X 2KBX 3F6Q 4HI8 4HI9 6MIF 7D2S 7D2T 7D2U
Enriched GO Terms of Interacting Partners?
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