CDC42EP4 and WDR6

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CDC42EP4	WDR6
Description		CDC42 effector protein 4	WD repeat domain 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Endomembrane System Actin Cytoskeleton Microtubule Cytoskeleton Phagocytic Vesicle	Cytoplasm Cytosol Plasma Membrane
	Molecular Function	RNA Binding Protein Binding Small GTPase Binding	RNA Binding Protein Binding Insulin Receptor Substrate Binding
	Biological Process	Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Cellular Response To Interferon-gamma	Cell Cycle Negative Regulation Of Cell Population Proliferation Negative Regulation Of Autophagy TRNA Methylation Regulation Of Cell Cycle
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle	RHOU GTPase cycle RHOV GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS			Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Menarche (age at onset) ( 25231870) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		9 interacting genes: APP BRD2 CDC42 FAM9B LNX1 RHOQ SRPK2 TGFBR1 WDR6	6 interacting genes: BRCA1 CDC42EP4 G2E3 GRIP1 PTPN3 SCAP
Entrez ID		23580	11180
HPRD ID		08383	06912
Ensembl ID		ENSG00000179604	ENSG00000178252
Uniprot IDs		B2R6D8 Q9H3Q1	A0A087X295 B3KRR8 B4E256 E9PDU5 Q9H9M3 Q9NNW5
PDB IDs
Enriched GO Terms of Interacting Partners?
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