FOS and RPS6KA2

  • Number of citations of the paper that reports this interaction (PubMedID 7623830)
  • 39
  • Data Source:
  • BioGRID (enzymatic study)

FOS

RPS6KA2

Description Fos proto-oncogene, AP-1 transcription factor subunit ribosomal protein S6 kinase A2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • Inflammatory bowel disease ( 23128233)
  • Periodontal microbiota ( 22699663)
  • 3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134)
  • Alzheimer's disease progression score ( 29860282)
  • Bipolar disorder ( 31043756)
  • Bipolar I disorder ( 31043756)
  • Blood pressure (smoking interaction) ( 25189868)
  • Café-au-lait macule number in neurofibromatosis type1 ( 32869517)
  • Dental caries ( 23259602)
  • HDL cholesterol levels in HIV infection ( 33109212)
  • Inflammatory bowel disease ( 27569725 23128233)
  • Macrovascular complications in type 2 diabetes ( 33430853)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
  • Smooth-surface caries ( 24556642)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
  • Waist circumference ( 28552196)
Interacting Genes 123 interacting genes: AKAP5 ANP32E APP AQP1 ARFGAP1 ARL6IP4 ATF2 ATF3 ATF4 ATF7 ATP5ME BATF BCL3 CABP1 CARM1 CCDC120 CCND1 CEBPA CEBPE CEBPG CENPO CFAP57 CLU COPS4 CREB5 CREBBP CSNK2A1 CSNK2A2 CYTH4 DDIT3 DNMT3L DYNLT3 EEF1D ELK1 ELK4 ENKD1 EPHB2 ETS1 ETS2 FHL3 GAMT GATA4 GLB1 GNG11 GRHPR GTF2E2 GTF2F1 GTF2F2 HMGB1 HNF1A HSPA1A JUN JUNB JUND KDM2A KDM2B LMNA LMO3 LUZP4 MAF MAFB MAFF MAP1B MAP3K7 MAPK1 MAPK3 MAPK7 MDM2 MITF MTERF4 NACA NCOA1 NCOA2 NCOA3 NCOA6 NCOR2 NEFM NELFB NFATC3 NFKB1 OPTN PIN1 PML POLR2E PRKAA2 PRKACA PRKAR2A PSMC5 RB1 RELA RPS6KA1 RPS6KA2 RPS6KA4 RUNX1 RUNX2 SCHIP1 SET SIRT1 SMAD3 SMARCD1 SPI1 SRA1 STAT1 SUMO1 SUMO2 SUMO3 SUMO4 TAF1 TBP TENT5B TP53 TRO TSC22D3 TSPAN2 UBE2D1 UBE2I UBE2L3 UBR1 USF1 USF2 VDR XBP1 ZNF133 19 interacting genes: AFDN BAD CREB1 DYNLT1 DYNLT2 FLNC FOS JUN KCNJ6 L1CAM MAGI1 MAP2K1 MAPK1 MAPK3 OTUD4 SHANK1 TBXT THBS2 TP53
Entrez ID 2353 6196
HPRD ID 01275 03403
Ensembl ID ENSG00000170345 ENSG00000071242
Uniprot IDs P01100 Q6FG41 B7Z3B5 Q15349 X5D337
PDB IDs 1A02 1FOS 1S9K
Enriched GO Terms of Interacting Partners?
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