FOLR1 and SLC35F6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FOLR1	SLC35F6
Description		folate receptor alpha	solute carrier family 35 member F6
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Endosome Endoplasmic Reticulum Membrane Plasma Membrane Cell Surface ER To Golgi Transport Vesicle Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Transport Vesicle Clathrin-coated Vesicle Anchored Component Of External Side Of Plasma Membrane Brush Border Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Extracellular Exosome	Nucleoplasm Mitochondrion Lysosomal Membrane Cytosol Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding Folic Acid Binding Signaling Receptor Activity Methotrexate Binding Folic Acid Receptor Activity	Protein Binding Transmembrane Transporter Activity
	Biological Process	Heart Looping Neural Crest Cell Migration Involved In Heart Formation Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Receptor-mediated Endocytosis Cell Adhesion Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Folic Acid Transport Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Axon Regeneration Sperm-egg Recognition Folic Acid Metabolic Process Regulation Of Canonical Wnt Signaling Pathway Pharyngeal Arch Artery Morphogenesis Anterior Neural Tube Closure Cellular Response To Folic Acid Folate Import Across Plasma Membrane	Positive Regulation Of Cell Population Proliferation Transmembrane Transport Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport
Drugs		Folic acid Vintafolide Farletuzumab
Diseases
GWAS			Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		8 interacting genes: CUL3 INTS4 IRAK3 LTB4R2 LYN NCAPH2 PDE2A SLC35F6	22 interacting genes: ACP5 ACP6 ALDH2 AQP6 CBARP CERS4 FOLR1 GJA8 GPR152 KIAA0087 KIAA0232 MS4A7 NDUFA4L2 NSG2 OAT PSMG2 SEC11A SEPHS1 SERPINH1 TBPL1 TIMMDC1 TMEM14B
Entrez ID		2348	54978
HPRD ID		00638	12808
Ensembl ID		ENSG00000110195	ENSG00000213699
Uniprot IDs		A0A024R5H1 P15328	Q8N357
PDB IDs		4KM6 4KM7 4KMX 4LRH 5IZQ
Enriched GO Terms of Interacting Partners?
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