ISCU and FAM9B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		ISCU	FAM9B
Description		iron-sulfur cluster assembly enzyme	family with sequence similarity 9 member B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol	Synaptonemal Complex Nucleoplasm
	Molecular Function	Iron Ion Binding Protein Binding Ferrous Iron Binding 2 Iron, 2 Sulfur Cluster Binding Molecular Adaptor Activity	Protein Binding
	Biological Process	Cellular Iron Ion Homeostasis Iron-sulfur Cluster Assembly Positive Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Aconitate Hydratase Activity Negative Regulation Of Iron Ion Import Across Plasma Membrane	Spermatid Development Meiotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Intraocular pressure ( 29617998)	Age at voice drop ( 27182965) Androgen levels ( 22936694) Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 30598549 28869591) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 29146897 27182965) Metabolite levels ( 23823483)
Interacting Genes		18 interacting genes: AGTRAP BANP CBY2 CCDC136 CCDC172 FAM9B GOLGA2 GOLGA6L9 HPRT1 IKZF1 JUN KRT34 KRT40 LNX1 MID2 NECAB2 NUP62 PICK1	142 interacting genes: ABT1 ACP6 ANKRD36B AP1M1 ASB6 ATF7 AURKAIP1 BAG6 BAIAP2L2 BARD1 BCL2A1 BET1 BLOC1S2 BRME1 BYSL C16orf72 C8orf33 CADPS CCDC106 CCDC116 CCDC198 CCDC70 CDC23 CDC37 CDC42EP4 CDCA7L CDSN CENPL CEP57L1 CEP95 CHRAC1 CLCN1 CMTM6 COL20A1 CSDE1 CWF19L2 DAPK2 DAXX DENND2D DGUOK DNAJC15 DNAJC4 EBNA1BP2 ECH1 EIF3G ELOA FAM161A FAM9A FASTKD3 FCHSD2 FERD3L FNDC11 GFOD1 GOPC GPX1 GRAMD4 GSTK1 HNRNPLL IBSP ISCU JAZF1 LBX1 LIN7A LINC02363 LMNA LNX1 LYRM2 MAB21L3 MFAP1 MOB1A MORF4L1 MORF4L2 MRPL10 MRPL28 MRPL9 MRRF MYG1 MYO15B NDE1 NDUFB10 NEBL NOL4 NOTO PAGE1 PAGE3 PHYH PIN4 POLL PPARA PPP1R18 PRPF3 PSMD14 PTRH1 RAB17 RAD51B RBM17 RBM23 RMND1 RNF8 RPL9 RSL24D1 RUBCN RUSC1 SDCBP SDCBP2 SERPINE2 SFN SLC16A3 SLPI SMARCB1 SMN1 SMN2 SNAP29 SNAP47 SNX20 SRRM4 STK3 SUCLA2 SURF6 SYT17 TBC1D25 TBRG4 TCEA2 TCEANC TGFBI TOM1L2 TRMT61B TSG101 TUFM TXN2 UBE2E2 URB1-AS1 WT1 XRCC4 YARS2 ZCCHC10 ZGPAT ZNF41 ZNF410 ZNF567 ZNF614 ZNF777
Entrez ID		23479	171483
HPRD ID		14828	15955
Ensembl ID		ENSG00000136003	ENSG00000177138
Uniprot IDs		A0A024RBI3 B1P7G3 B3KQ30 B4DNC9 Q9H1K1	A0A024RBV3 Q8IZU0
PDB IDs		5KZ5 5WKP 5WLW 6NZU 6UXE 6W1D 6WI2 6WIH
Enriched GO Terms of Interacting Partners?
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