HEY1 and FBXW7

  • Number of citations of the paper that reports this interaction (PubMedID 11585921)
  • 116
  • Data Source:
  • HPRD (in vivo)

HEY1

FBXW7

Description hes related family bHLH transcription factor with YRPW motif 1 F-box and WD repeat domain containing 7
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699)
  • Eosinophil counts ( 32888494)
  • Eosinophil percentage of white cells ( 32888494)
Interacting Genes 24 interacting genes: ARNT CREBZF DAZAP2 FBXW7 FOXH1 GATA1 HES1 HEY2 KRTAP6-2 LAPTM5 MDM2 MYOD1 NTRK3 PITX2 PLEKHB2 PLEKHF2 PRKD2 SKIL SMAD3 SMAD9 TENT5D THTPA TP53 YTHDF1 84 interacting genes: ACD AHSG AKT1 ANGPTL4 ANP32B ARL6IP1 BCAS3 BEX1 BLM CCDC6 CCNE1 CCNE2 CDC34 CEBPD CUL1 DISC1 DVL1 EBNA1BP2 EXT1 EZH2 FANCC FBP1 FBP2 FBXO45 GALNT12 GATA2 GATA3 GFI1 GLMN HEMGN HEY1 HIPK2 HNRNPK HRAS IGFBP3 IL24 JUN KLF10 KLF5 KMT2D LINGO1 MAP2K1 MAPK3 MMS22L MYB MYC MYCN NANS NOTCH1 NOTCH4 NPM1 PLK1 PPARGC1A PPP3R2 PRKN PSEN1 PTPN11 RACK1 RFLNA SCGB3A1 SEC61B SHC1 SHOC2 SHPRH SIK2 SKP1 SMAD1 SOX9 SP7 SPI1 SREBF1 STAT3 STAT5A STOML1 STYX SUMF2 TGFB1 TMOD1 TP53 TSC22D4 USP9X WDR97 XPA ZNF510
Entrez ID 23462 55294
HPRD ID 04260 05888
Ensembl ID ENSG00000164683 ENSG00000109670
Uniprot IDs B4DEI9 Q9Y5J3 G0Z2K0 Q969H0 S4R3U4
PDB IDs 2DB7 2OVP 2OVQ 2OVR 5IBK 5V4B
Enriched GO Terms of Interacting Partners?
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