FBXW7 and ANGPTL4

  • Number of citations of the paper that reports this interaction (PubMedID 25640309)
  • 8
  • Data Source:
  • BioGRID (two hybrid)

FBXW7

ANGPTL4

Description F-box and WD repeat domain containing 7 angiopoietin like 4
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Eosinophil counts ( 32888494)
  • Eosinophil percentage of white cells ( 32888494)
  • Apolipoprotein A1 levels ( 32203549)
  • Coronary artery disease ( 29212778)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • HDL cholesterol ( 24097068 28270201 24507774 19060906 30275531 25961943 20686565)
  • HDL cholesterol levels ( 32203549 28334899 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
  • HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • High density lipoprotein cholesterol levels ( 33339817)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Mean spheric corpuscular volume ( 32888494)
  • Metabolic syndrome ( 31589552)
  • Metabolite levels (lipoprotein measures) ( 27005778)
  • Myocardial infarction ( 33532862)
  • Phospholipid levels in large HDL ( 29084231)
  • Red cell distribution width ( 32888494)
  • Reticulocyte count ( 32888494)
  • Reticulocyte fraction of red cells ( 32888494)
  • Total cholesterol levels in HDL ( 29084231)
  • Total triglycerides levels ( 29084231)
  • Triglyceride levels ( 32203549 32154731 33339817 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglycerides ( 24507774 30275531 25961943 27036123)
  • Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes 84 interacting genes: ACD AHSG AKT1 ANGPTL4 ANP32B ARL6IP1 BCAS3 BEX1 BLM CCDC6 CCNE1 CCNE2 CDC34 CEBPD CUL1 DISC1 DVL1 EBNA1BP2 EXT1 EZH2 FANCC FBP1 FBP2 FBXO45 GALNT12 GATA2 GATA3 GFI1 GLMN HEMGN HEY1 HIPK2 HNRNPK HRAS IGFBP3 IL24 JUN KLF10 KLF5 KMT2D LINGO1 MAP2K1 MAPK3 MMS22L MYB MYC MYCN NANS NOTCH1 NOTCH4 NPM1 PLK1 PPARGC1A PPP3R2 PRKN PSEN1 PTPN11 RACK1 RFLNA SCGB3A1 SEC61B SHC1 SHOC2 SHPRH SIK2 SKP1 SMAD1 SOX9 SP7 SPI1 SREBF1 STAT3 STAT5A STOML1 STYX SUMF2 TGFB1 TMOD1 TP53 TSC22D4 USP9X WDR97 XPA ZNF510 9 interacting genes: AURKA BRMS1 CASP8 CDKN2A CDKN2C ESR1 FBXW7 FGFR4 TGFB1
Entrez ID 55294 51129
HPRD ID 05888 16173
Ensembl ID ENSG00000109670 ENSG00000167772
Uniprot IDs G0Z2K0 Q969H0 S4R3U4 Q9BY76
PDB IDs 2OVP 2OVQ 2OVR 5IBK 5V4B 6EUB 6U0A 6U1U 6U73
Enriched GO Terms of Interacting Partners?
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