GRIP1 and AGAP2

Number of citations of the paper that reports this interaction (PubMedID 21847098)
19

Data Source:
BioGRID (pull down)

		GRIP1	AGAP2
Description		glutamate receptor interacting protein 1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Postsynaptic Density Dendrite Cytoplasmic Vesicle Neuron Projection Perikaryon Membrane Raft Postsynaptic Membrane Glutamatergic Synapse	Nucleus Nucleoplasm Cytoplasm Endosome Cytosol Membrane Extracellular Exosome Flemming Body
	Molecular Function	Protein Binding Beta-catenin Binding Protein C-terminus Binding Signaling Receptor Complex Adaptor Activity Glucocorticoid Receptor Binding	GTPase Activity GTPase Activator Activity Protein Binding ATP Binding GTP Binding Protein Kinase Binding Protein Kinase Activator Activity Phosphatidylinositol 3-kinase Regulator Activity Metal Ion Binding
	Biological Process	Dendrite Development Intracellular Signal Transduction Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Positive Regulation Of Neuron Projection Arborization	Protein Transport Endosomal Transport Actin Cytoskeleton Organization Activation Of Protein Kinase Activity Negative Regulation Of Protein Catabolic Process Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Protein Kinase Activity Positive Regulation Of 1-phosphatidylinositol-3-kinase Activity
Pathways		Trafficking of GluR2-containing AMPA receptors	Netrin-1 signaling
Drugs
Diseases
GWAS		Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Post bronchodilator FEV1/FVC ratio ( 26634245)	Heel bone mineral density ( 30598549) Multiple sclerosis ( 21833088)
Interacting Genes		44 interacting genes: AGAP2 AR CARM1 CSPG4 DEPDC1B DZIP3 EEPD1 EFNA5 EFNB1 EFNB2 EP300 ESR1 FGF12 FLII FXR1 FXR2 GPR37 GRIA1 GRIA3 GRIA4 GRIK1 GRIK2 GRIPAP1 GRM2 GRM3 GRM7 H3C1 HUS1 IRF3 MFAP3 NCOA6 NEK6 NR3C1 NUMBL PICK1 PPARG PRKD2 PRMT1 RXRA THRA UBE2I VDR WDR6 XDH	16 interacting genes: AKT1 ARF1 CDC42 CDK4 EPB41L1 GRIP1 HOMER1 HOMER2 NF2 PIK3R1 PLCG1 PRKAA1 RAC1 RAC2 RHOA TBK1
Entrez ID		23426	116986
HPRD ID		19086	05687
Ensembl ID		ENSG00000155974	ENSG00000135439
Uniprot IDs		Q9Y3R0	A0A024RB55 F8VVT9 Q99490
PDB IDs		2JIL	2BMJ 2IWR 2RLO
Enriched GO Terms of Interacting Partners?
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