AGAP2 and EPB41L1

Number of citations of the paper that reports this interaction (PubMedID 11136977)
62

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		AGAP2	EPB41L1
Description		ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	erythrocyte membrane protein band 4.1 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endosome Cytosol Membrane Extracellular Exosome Flemming Body	Cytosol Cytoskeleton Plasma Membrane
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding ATP Binding GTP Binding Protein Kinase Binding Protein Kinase Activator Activity Phosphatidylinositol 3-kinase Regulator Activity Metal Ion Binding	Actin Binding Structural Molecule Activity Protein Binding
	Biological Process	Protein Transport Endosomal Transport Actin Cytoskeleton Organization Activation Of Protein Kinase Activity Negative Regulation Of Protein Catabolic Process Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Protein Kinase Activity Positive Regulation Of 1-phosphatidylinositol-3-kinase Activity	Cortical Actin Cytoskeleton Organization Actomyosin Structure Organization
Pathways		Netrin-1 signaling	Trafficking of AMPA receptors Neurexins and neuroligins Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Multiple sclerosis ( 21833088)	Basal cell carcinoma ( 33549134) Height ( 23563607) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 34021172) Keratinocyte cancer (MTAG) ( 31174203) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		16 interacting genes: AKT1 ARF1 CDC42 CDK4 EPB41L1 GRIP1 HOMER1 HOMER2 NF2 PIK3R1 PLCG1 PRKAA1 RAC1 RAC2 RHOA TBK1	19 interacting genes: AGAP2 APP ARHGAP1 CHRM5 DRD2 DRD3 GRIA1 GRIA4 HSPB1 ITPR1 NR3C1 NUMA1 POT1 SRPK2 STARD13 TERF1 YWHAB YWHAQ YWHAZ
Entrez ID		116986	2036
HPRD ID		05687	04193
Ensembl ID		ENSG00000135439	ENSG00000088367
Uniprot IDs		A0A024RB55 F8VVT9 Q99490	A0A0C4DH22 B7Z653 Q9H4G0
PDB IDs		2BMJ 2IWR 2RLO
Enriched GO Terms of Interacting Partners?
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