NEDD4L and MAPKAPK3

  • Number of citations of the paper that reports this interaction (PubMedID 19953087)
  • 57
  • Data Source:
  • BioGRID (enzymatic study)

NEDD4L

MAPKAPK3

Description NEDD4 like E3 ubiquitin protein ligase MAPK activated protein kinase 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 28240269)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025)
  • Cortical surface area (MOSTest) ( 32665545)
  • Depressive symptom (appetite changes) (binary trait) ( 31530331)
  • Depressive symptoms (binary sum-score) ( 31530331)
  • Depressive symptoms (sum-score) ( 31530331)
  • High light scatter reticulocyte count ( 32888494)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
Interacting Genes 139 interacting genes: AATF ABL1 ABL2 ACVR1B ACY3 ADAP2 AICDA AKT3 AMOT APEX2 ARHGDIA ARRDC3 AURKC BBX BMPR1A C7orf50 CACNB1 CAMK1D CDC34 CDK3 CDK5 CLIC2 CUEDC1 CYBRD1 CYP26B1 DAPK3 DAZAP2 DDX54 DECR2 DMTN DYRK3 EFEMP2 FGF12 FKBP3 FOXO1 GORAB GRIA1 H1-0 HAX1 IFRD2 IKBKB KCNAB1 KCNAB2 KCNAB3 KCNB1 KIF3B KIFC3 LAPTM5 MAGEB1 MAP2 MAP3K2 MAP3K20 MAP3K3 MAP3K5 MAPKAPK3 MARK2 MERTK MINK1 MOB3A MRPL19 NDFIP2 NEAT1 NHP2 NR3C1 NSRP1 NTRK1 NUDT16L1 OGG1 PBX1 PIK3CA PIP4P2 PRKX PRR16 PRRG1 PRRG2 PRRG4 PSMD4 PYM1 RANBP10 RASL10B RASL11B RHOB RNF11 RNF7 ROBO3 RPL30 RPS6KB2 SCAMP3 SCD SCN5A SCNN1A SCNN1B SCNN1G SENP2 SERPINF1 SGK1 SGK2 SIVA1 SLC7A7 SMAD2 SMAD3 SMAD7 SNCA SP1 SPAG8 SRMS STAC STK40 TAF1B TARBP2 TBC1D7 TCEAL2 TGFB1I1 TMA16 TRIM41 UBAC1 UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2J2 UBE2K UBE2L3 UBE2L6 UBE2N ULK1 USP7 VDAC2 WBP2 WNK4 YWHAG YWHAZ YY1 ZADH2 ZC3HAV1L ZDHHC3 22 interacting genes: APP ATF1 BECN1 CHMP2A COPS6 EEF2 EEF2K EZH2 HSPB1 IGHM LINC02582 MAPK13 MAPK14 NEDD4 NEDD4L RAB2A RCSD1 SMS SRPK2 SUMO3 TCF3 THAP12
Entrez ID 23327 7867
HPRD ID 05903 03678
Ensembl ID ENSG00000049759 ENSG00000114738
Uniprot IDs A0A024R281 A0A024R2A4 B7Z2P9 B7Z6K0 Q96PU5 A0A024R2W7 Q16644
PDB IDs 2LAJ 2LB2 2LTY 2MPT 2NSQ 2ONI 3JVZ 3JW0 5HPK 3FHR 3FXW 3R1N 3SHE
Enriched GO Terms of Interacting Partners?
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