TRIM2 and UBE2K

  • Number of citations of the paper that reports this interaction (PubMedID 19549727)
  • 74
  • Data Source:
  • BioGRID (two hybrid)

TRIM2

UBE2K

Description tripartite motif containing 2 ubiquitin conjugating enzyme E2 K
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein A1 levels ( 32203549)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • HDL cholesterol ( 30275531)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Heel bone mineral density ( 30598549)
  • LDL cholesterol levels ( 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Liver enzyme levels (alkaline phosphatase) ( 33972514)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Multiple sclerosis ( 21654844)
  • Thyrotoxic periodic paralysis ( 33105104)
  • Apolipoprotein A1 levels ( 32203549)
  • HDL cholesterol levels ( 32203549)
  • Plasma amyloid beta peptide concentrations (ABx-40) ( 24535457)
  • Platelet count ( 32888494)
Interacting Genes 28 interacting genes: BCL2L11 CDK20 CIB3 COG3 DTNBP1 GJB5 KCTD7 LRRC8E MNAT1 MYO5A OTUB2 SIRPA TNFAIP3 TNIK TRIM3 TRIM8 UBAC1 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2U UBE2W 94 interacting genes: AMFR ANAPC11 BARD1 BFAR BIRC7 BIRC8 BRCA1 CASP12 CBLC CCNC CDC6 DDI1 DIABLO DTX3 DTX3L DZIP3 EXOSC7 FZR1 HTT ITCH ITSN1 KRIT1 LRSAM1 MAP3K1 MARCHF3 MARCHF7 MDM2 MEOX2 MID1 MID2 MIPOL1 MKRN2 MKRN3 NEDD4L NEDD8 NFKB1 NUB1 PAX6 PIAS4 PICK1 PJA1 PRKN PRPF40A PRRG4 RBCK1 RC3H2 REL RING1 RLIM RNF111 RNF114 RNF125 RNF138 RNF144A RNF166 RNF167 RNF182 RNF183 RNF185 RNF2 RNF31 RNF32 RNF4 RNF41 RNF5 SDCBP SENP1 SH3RF1 SIAH1 SMURF1 TP53 TRAF7 TRAIP TRIM2 TRIM27 TRIM3 TRIM31 TRIM34 TRIM35 TRIM39 TRIM43 TRIM5 TRIM50 TRIM63 TSN UBA1 UBB UBE2I UBOX5 UHRF2 USP1 WWP2 ZDHHC17 ZNF384
Entrez ID 23321 3093
HPRD ID 10279 04165
Ensembl ID ENSG00000109654 ENSG00000078140
Uniprot IDs A0A0J9YW02 A0A6Q8PF63 A0A6Q8PFB0 A0A6Q8PG16 Q9C040 B3KSH4 B4DIZ2 P61086
PDB IDs 7B2R 1YLA 2O25 3E46 3F92 3K9O 3K9P 5DFL 6IF1 6JB6 6JB7
Enriched GO Terms of Interacting Partners?
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