ATG4B and MAP1LC3A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid, enzymatic study)

		ATG4B	MAP1LC3A
Description		autophagy related 4B cysteine peptidase	microtubule associated protein 1 light chain 3 alpha
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GO Annotations	Cellular Component	Cytosol	Autophagosome Membrane Late Endosome Autophagosome Cytosol Microtubule Organelle Membrane Intracellular Membrane-bounded Organelle Autolysosome Synapse
	Molecular Function	Endopeptidase Activity Cysteine-type Endopeptidase Activity Protein Binding Cysteine-type Peptidase Activity Scaffold Protein Binding	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding
	Biological Process	Proteolysis Autophagy Protein Transport Macroautophagy Positive Regulation Of Protein Catabolic Process Protein Delipidation	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Response To Iron(II) Ion Response To Lead Ion Macroautophagy Cellular Response To Amino Acid Starvation Response To Morphine Cellular Response To Hydrogen Peroxide Cellular Response To Copper Ion Autophagosome Maturation
Pathways		Macroautophagy	Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy
Drugs
Diseases
GWAS		Asthma ( 31959851) Body mass index ( 29273807) Carotid intima media thickness ( 30510157) Crohn's disease ( 26192919) Prostate cancer ( 23535732)	Alanine aminotransferase levels ( 33547301) Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241) Fish- and plant-related diet ( 32066663) Hip circumference adjusted for BMI ( 34021172) Oily fish consumption ( 32066663) Pork consumption ( 32066663)
Interacting Genes		5 interacting genes: GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B	56 interacting genes: AKAP13 AMBRA1 ANK2 ANK3 APP ATG13 ATG4B ATG7 ATXN3 BNIP3L DVL2 EPHA7 FUNDC1 GPSM1 IRGQ KIF15 KXD1 LMNB1 MAP1A MAP1S MAVS MDM2 MEFV MREG NBR1 NEDD4 OPRM1 OPTN PHB PHB2 PIAS4 PRPF40A RABGAP1 RABGAP1L RDH12 RETREG3 RTKN SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TP53INP1 TRIM21 TRIM32 TUBA4A VPS9D1
Entrez ID		23192	84557
HPRD ID		16499	03144
Ensembl ID		ENSG00000168397	ENSG00000101460
Uniprot IDs		B3KVU2 Q9Y4P1	Q9H492
PDB IDs		2CY7 2D1I 2Z0D 2Z0E 2ZZP 5LXH 5LXI	3ECI 3WAL 3WAN 4ZDV 5CX3 5DPR 6TBE
Enriched GO Terms of Interacting Partners?
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