MAP1LC3A and AKAP13

Number of citations of the paper that reports this interaction (PubMedID 19696020)
11

Data Source:
BioGRID (pull down)

		MAP1LC3A	AKAP13
Description		microtubule associated protein 1 light chain 3 alpha	A-kinase anchoring protein 13
Image
GO Annotations	Cellular Component	Autophagosome Membrane Late Endosome Autophagosome Cytosol Microtubule Organelle Membrane Intracellular Membrane-bounded Organelle Autolysosome Synapse	Nucleus Cytosol Cell Cortex Actin Cytoskeleton Membrane Cortical Actin Cytoskeleton Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding	CAMP-dependent Protein Kinase Activity MAP-kinase Scaffold Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Small GTPase Binding Metal Ion Binding Protein Kinase A Binding Molecular Adaptor Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Response To Iron(II) Ion Response To Lead Ion Macroautophagy Cellular Response To Amino Acid Starvation Response To Morphine Cellular Response To Hydrogen Peroxide Cellular Response To Copper Ion Autophagosome Maturation	Protein Phosphorylation G Protein-coupled Receptor Signaling Pathway Heart Development Regulation Of Rho Protein Signal Transduction Positive Regulation Of Rho Protein Signal Transduction Intracellular Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAP Kinase Activity Regulation Of Small GTPase Mediated Signal Transduction Nuclear Export Cardiac Muscle Cell Differentiation Regulation Of Sarcomere Organization Bone Development Cell Growth Involved In Cardiac Muscle Cell Development Adrenergic Receptor Signaling Pathway Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process
Pathways		Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy	NRAGE signals death through JNK G alpha (12/13) signalling events RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241) Fish- and plant-related diet ( 32066663) Hip circumference adjusted for BMI ( 34021172) Oily fish consumption ( 32066663) Pork consumption ( 32066663)	Birth weight ( 31043758) Body shape index ( 34021172) Central corneal thickness ( 32528159 31798171 29760442 20719862) Corneal structure ( 23291589) Coronary artery disease ( 29212778) Granulocyte percentage of myeloid white cells ( 27863252) Hemoglobin ( 32888494) High myopia ( 32428537) Idiopathic pulmonary fibrosis ( 31710517 29066090) Immature fraction of reticulocytes ( 32888494) Intraocular pressure ( 29617998) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Medication use (diuretics) ( 31015401) Metabolite levels ( 23823483) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 31604244) Neutrophil percentage of white cells ( 32888494) Offspring birth weight ( 31043758) Platelet count ( 32888494) Platelet distribution width ( 32888494) Post-bronchodilator lung function in asthma (FEV1/FVC) ( 32989782) Psoriasis ( 25939698) Pulse pressure ( 30578418) Red blood cell count ( 32888494) Refractive error ( 32231278) Response to platinum-based chemotherapy (carboplatin) ( 21844884) Systolic blood pressure ( 30578418) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		56 interacting genes: AKAP13 AMBRA1 ANK2 ANK3 APP ATG13 ATG4B ATG7 ATXN3 BNIP3L DVL2 EPHA7 FUNDC1 GPSM1 IRGQ KIF15 KXD1 LMNB1 MAP1A MAP1S MAVS MDM2 MEFV MREG NBR1 NEDD4 OPRM1 OPTN PHB PHB2 PIAS4 PRPF40A RABGAP1 RABGAP1L RDH12 RETREG3 RTKN SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TP53INP1 TRIM21 TRIM32 TUBA4A VPS9D1	21 interacting genes: APP CTNNAL1 ESR1 ESR2 GNA12 GNAQ LINC00839 MAP1LC3A PPARA PRKAR2A PRKD1 RANBP2 RHOA RTKN RXRB SRPK2 THRA YWHAB YWHAE YWHAG YWHAZ
Entrez ID		84557	11214
HPRD ID		03144	05253
Ensembl ID		ENSG00000101460	ENSG00000170776
Uniprot IDs		Q9H492	A8MYJ1 B0AZU4 Q12802
PDB IDs		3ECI 3WAL 3WAN 4ZDV 5CX3 5DPR 6TBE	2DRN 2LG1 4D0N 4D0O 6BCA
Enriched GO Terms of Interacting Partners?
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