SEPTIN8 and KMT2B

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		SEPTIN8	KMT2B
Description		septin 8	lysine methyltransferase 2B
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GO Annotations	Cellular Component	Septin Ring Microtubule Cytoskeleton Axon Synaptic Vesicle Membrane Septin Complex Cell Division Site Presynapse	Nucleus Nucleoplasm Histone Methyltransferase Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding Molecular Adaptor Activity	Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K4 Specific) Unmethylated CpG Binding
	Biological Process	Cellular Protein Localization Regulation Of SNARE Complex Assembly Cytoskeleton-dependent Cytokinesis	Histone H3-K4 Dimethylation Positive Regulation Of Transcription, DNA-templated Histone H3-K4 Methylation Histone H3-K4 Monomethylation
Pathways			PKMTs methylate histone lysines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Eosinophil percentage of white cells ( 32888494) Refractive error ( 32231278)
Interacting Genes		12 interacting genes: A2M ACSL6 CDK14 ESR1 JADE1 KMT2B PPHLN1 SEPTIN4 SEPTIN5 SH3GL1 SH3GL3 SPTBN1	27 interacting genes: ANXA1 ANXA7 ASH2L ATP1B1 ATXN1 CDKN1A GRB7 H3C1 H3C14 MTDH NREP PIK3R3 PIN1 PRPF40A RAP1B RBBP5 RCC1 RPP14 SEPTIN8 SMAD3 SMARCB1 SMN1 TK1 TRIM55 TRIM63 TSC22D1 ZNF512B
Entrez ID		23176	9757
HPRD ID		12228	06017
Ensembl ID		ENSG00000164402	ENSG00000272333
Uniprot IDs		A6NFQ9 B7ZVZ1 Q92599	Q9UMN6
PDB IDs		6UPR	3UVM 4ERZ 4PZI 7BRE
Enriched GO Terms of Interacting Partners?
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