LPIN1 and RRM2

		LPIN1	RRM2
Description		lipin 1	ribonucleotide reductase regulatory subunit M2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Cytosol Nuclear Membrane	Cytosol Ribonucleoside-diphosphate Reductase Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding Phosphatidate Phosphatase Activity	Ribonucleoside-diphosphate Reductase Activity, Thioredoxin Disulfide As Acceptor Protein Binding Ferric Iron Binding Protein Homodimerization Activity
	Biological Process	DNA Replication Triglyceride Mobilization Phosphatidic Acid Biosynthetic Process Mitotic Nuclear Membrane Disassembly Fatty Acid Catabolic Process Dephosphorylation Triglyceride Biosynthetic Process Animal Organ Regeneration Negative Regulation Of Myelination Cellular Response To Insulin Stimulus Cellular Lipid Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cold-induced Thermogenesis Regulation Of Phosphatidate Phosphatase Activity	Blastocyst Development DNA Replication Deoxyribonucleotide Biosynthetic Process Protein Heterotetramerization
Pathways		Synthesis of PC Synthesis of PE Depolymerisation of the Nuclear Lamina Triglyceride biosynthesis	Interconversion of nucleotide di- and triphosphates G1/S-Specific Transcription Transcriptional Regulation by E2F6
Drugs			Cladribine Imexon Gallium nitrate Motexafin gadolinium GTI 2040
Diseases
GWAS		Chronotype ( 30696823) Metabolite levels ( 23823483) Post bronchodilator percent predicted FEV1 in smoking ( 30068317)	Kidney function decline traits ( 25493955) Prostate cancer ( 23535732)
Interacting Genes		2 interacting genes: CDK6 RRM2	19 interacting genes: ASAP2 BARX1 CDH1 CDK1 DNM1L GCG ITSN2 KAT5 LAPTM4A LPIN1 MGAT4A NPBWR2 PLK3 RRM1 RRM2B SDCBP ST3GAL3 TAF1B TP53
Entrez ID		23175	6241
HPRD ID		09271	01587
Ensembl ID		ENSG00000134324	ENSG00000171848
Uniprot IDs		Q14693	P31350
PDB IDs			2UW2 3OLJ 3VPM 3VPN 3VPO
Enriched GO Terms of Interacting Partners?
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