CAND2 and DNAJB6

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		CAND2	DNAJB6
Description		cullin associated and neddylation dissociated 2 (putative)	DnaJ heat shock protein family (Hsp40) member B6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Z Disc Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding TBP-class Protein Binding	ATPase Activator Activity DNA Binding Protein Binding Heat Shock Protein Binding Protein Folding Chaperone Unfolded Protein Binding Chaperone Binding
	Biological Process	SCF Complex Assembly Protein Ubiquitination Positive Regulation Of Transcription, DNA-templated	Protein Folding Actin Cytoskeleton Organization Extracellular Matrix Organization Regulation Of Protein Localization Protein Localization To Nucleus Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Intermediate Filament Organization Negative Regulation Of Transcription, DNA-templated Chorio-allantoic Fusion Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Chorion Development Chaperone-mediated Protein Folding Negative Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat
Pathways			Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737 29892015) Creatine kinase levels ( 29403010) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) HOMA-B (corrected for HOMA-IR) ( 30369944) P wave duration ( 28794112) Waist circumference adjusted for body mass index ( 28552196) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Body mass index ( 28552196) Retinal detachment or retinal break ( 31816047) Waist circumference ( 28552196)
Interacting Genes		10 interacting genes: CIDEB CNOT3 DNAJB6 FHL2 GLP1R MRPS25 RBX1 SYP TBP UBE3C	23 interacting genes: ANKRD1 APP ASAP1 BRMS1 CAND2 DYSF EPHB4 KRT18 MAP3K1 MLF1 MRTO4 MYBPC1 MYOM1 PGM1 PIK3CA POLR1D PTEN SGCG SKAP2 SUPT6H TTN TUBGCP3 USP8
Entrez ID		23066	10049
HPRD ID		19120	07107
Ensembl ID		ENSG00000144712	ENSG00000105993
Uniprot IDs		O75155	A0A0J9YX62 O75190
PDB IDs			6U3R 6U3S 7JSQ
Enriched GO Terms of Interacting Partners?
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