TNIK and ANK2

  • Number of citations of the paper that reports this interaction (PubMedID 17043677)
  • 193
  • Data Source:
  • BioGRID (two hybrid)

TNIK

ANK2

Description TRAF2 and NCK interacting kinase ankyrin 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adolescent idiopathic scoliosis ( 28334814)
  • Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Cerebrospinal fluid AB1-42 levels ( 29274321)
  • Change in serum metabolite levels ( 31636271)
  • Change in serum metabolite levels (CMS) ( 31636271)
  • Cortical surface area (MOSTest) ( 32665545)
  • Estimated glomerular filtration rate after 1 year in renal transplantation (recipient effect) ( 30920136)
  • Frontotemporal dementia (age at onset) ( 29724592)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Hip circumference adjusted for BMI ( 28552196)
  • LDL cholesterol ( 21347282)
  • Lymphocyte counts ( 32888494 27863252)
  • Lymphocyte percentage of white cells ( 32888494)
  • Night sleep phenotypes ( 27126917)
  • Response to antipsychotic treatment in schizophrenia ( 29503163)
  • Subcortical volume (MOSTest) ( 32665545)
  • Triglyceride levels ( 32154731)
  • Type 2 diabetes ( 30054458)
  • Blood trace element (Cu levels) ( 23720494)
  • Body mass index ( 26426971)
  • Chronotype ( 30696823)
  • Diastolic blood pressure ( 31469255)
  • Fractional exhaled nitric oxide (childhood) ( 24315451)
  • Gut microbiota relative abundance (Coprococcus) ( 33208821)
  • Gut microbiota relative abundance (unclassified genus belonging to the order Clostridiales) ( 33208821)
  • Ischemic stroke ( 29531354)
  • Parkinson's disease ( 28892059)
  • Periventricular white matter hyperintensities ( 32517579)
  • Response to levetiracetam in genetic generalized epilepsy ( 32308125)
  • Stroke ( 29531354)
  • Systolic blood pressure and diastolic blood pressure (bivariate analysis) ( 33539483)
Interacting Genes 37 interacting genes: ACTG1 AGTPBP1 AKAP9 ANK2 CLU CNKSR2 DPYSL2 DPYSL3 DST DYNC1H1 GOLGA4 GSE1 GSN HARS1 MACF1 NCK1 NCOR2 NEDD4 NEFM PAFAH1B1 PDE4DIP PPM1E PPP1R13B RAP2A SMARCE1 SMURF1 SNX6 SOS1 SPTBN1 SRGAP3 SYNE1 TIAM2 TNKS TRAF2 TRIM2 TUBB2A WWC1 20 interacting genes: ANKRD28 DNAJB1 DNAJB5 ECPAS EPB42 GABARAP GABARAPL1 GABARAPL2 L1CAM MAP1LC3A MAP1LC3B MAP1LC3C NDEL1 NRCAM OBSCN SIGMAR1 SPTBN1 TAF9 TNIK TP53
Entrez ID 23043 287
HPRD ID 18206 00110
Ensembl ID ENSG00000154310 ENSG00000145362
Uniprot IDs Q9UKE5 Q01484
PDB IDs 2X7F 5AX9 5CWZ 5D7A 6RA5 6RA7 4D8O 4RLV 4RLY 5Y4D 5Y4E 5Y4F 5YIR 5YIS 6KZJ 6M3Q
Enriched GO Terms of Interacting Partners?
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