SCMH1 and SFMBT2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SCMH1	SFMBT2
Description		Scm polycomb group protein homolog 1	Scm like with four mbt domains 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromocenter	Nucleus Nucleoplasm Cytosol Aggresome Nuclear Body Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	Chromatin Binding Protein Binding Histone Binding	Chromatin Binding Transcription Corepressor Activity Protein Binding Histone Binding
	Biological Process	Chromatin Remodeling Spermatogenesis Anterior/posterior Pattern Specification Gene Silencing Negative Regulation Of Transcription, DNA-templated	Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs		Mercaptoethanol
Diseases
GWAS		Adventurousness ( 30643258) Appendicular lean mass ( 33097823) Atrial fibrillation ( 30061737 29892015) General risk tolerance (MTAG) ( 30643258) Height ( 20881960 25282103 23563607 18391952) Hip circumference adjusted for BMI ( 34021172) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Rapid response to perioperative phenylephrine (change in mean arterial pressure) ( 33168928)	Asthma (childhood onset) ( 31036433) Fasting blood insulin (BMI interaction) ( 22581228) Femoral neck bone mineral density ( 32239398) Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398) Monoclonal gammopathy of undetermined significance ( 30737484)
Interacting Genes		22 interacting genes: EWSR1 FXR1 FXR2 GMNN HK1 HPCAL4 LYPLA2 LZTR1 MAGEA12 MAML3 MOB4 PCBD1 PHC1 PHC2 POLR2M SFMBT1 SFMBT2 TMEM11 TOB1 TSC1 UBQLN1 UBQLN4	11 interacting genes: CLK1 L3MBTL3 LYPLA1 PHC1 SCMH1 SCML1 SCML2 SIAH1 SLF2 TFAP4 UBE2O
Entrez ID		22955	57713
HPRD ID		11540	18853
Ensembl ID		ENSG00000010803	ENSG00000198879
Uniprot IDs		B3KMZ7 Q96GD3	Q5VUG0
PDB IDs		2P0K	1WJR
Enriched GO Terms of Interacting Partners?
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