MAPRE3 and YAF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MAPRE3	YAF2
Description		microtubule associated protein RP/EB family member 3	YY1 associated factor 2
Image
GO Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Midbody Microtubule Plus-end Spindle Midzone Mitotic Spindle Astral Microtubule End	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Microtubule Binding Protein C-terminus Binding Protein Kinase Binding Identical Protein Binding Microtubule Plus-end Binding	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Protein Localization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule Polymerization Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Transcription, DNA-templated Spindle Assembly Cell Division Positive Regulation Of Microtubule Plus-end Binding Protein Localization To Microtubule Plus-end	Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways			RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Estimated glomerular filtration rate in non-diabetics ( 31451708) Leftâ€“right brain asymmetry ( 33723403) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Refractive error ( 32231278)
Interacting Genes		57 interacting genes: ANKRD1 APC2 AURKA AURKB C20orf202 C4orf45 CCSER1 CHRDL2 CLASP1 CRTAC1 DCTN2 DDIT4L DOK4 EIF4E2 FAM161B FOXD4L1 FOXD4L4 FXR2 GAS2L2 GTF2F2 GTSE1 HROB IKZF1 JUN KIF19 KLHDC7B KNSTRN LAP3 LHX4 LMO2 MAPRE2 MARCHF7 MEOX2 MRPL12 PDE4DIP PICK1 POU4F1 PSMA1 PSMB1 PSRC1 RAB1A REL SDCBP SIAH1 SLAIN1 SPDYE2 SPDYE2B TEX43 TLE5 TRAIP TRIM14 TXN2 YAF2 ZC2HC1A ZC2HC1C ZNF526 ZNF547	30 interacting genes: ANP32B CAVIN1 CD300LF DNAAF6 EAF1 GABPB1 IFT57 INO80B LGALS7 LGALS7B MAPRE3 MARK1 MYC MYCN NEDD8 NUTF2 PCDH17 POLR3GL PPP1R11 PTEN RING1 SETBP1 SPANXN2 SPANXN3 TBK1 TLK1 UBC XAGE1B YY1 ZFP42
Entrez ID		22924	10138
HPRD ID		16156	09606
Ensembl ID		ENSG00000084764	ENSG00000015153
Uniprot IDs		Q9UPY8	B4DJQ9 G3V212 Q8IY57
PDB IDs		1WYO 3CO1 3JAK 3JAL 3JAR 3TQ7	2D9G
Enriched GO Terms of Interacting Partners?
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