YAF2 and MARK1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		YAF2	MARK1
Description		YY1 associated factor 2	microtubule affinity regulating kinase 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Cytoplasm Cytoskeleton Plasma Membrane Microtubule Cytoskeleton Dendrite
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding	Magnesium Ion Binding Phosphatidylserine Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding Tau Protein Binding Tau-protein Kinase Activity Phosphatidic Acid Binding Protein Serine Kinase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated	Microtubule Cytoskeleton Organization Neuron Migration Protein Phosphorylation Cytoskeleton Organization Regulation Of Neuron Projection Development Wnt Signaling Pathway Peptidyl-serine Phosphorylation Intracellular Signal Transduction Regulation Of Dendrite Development Establishment Of Mitochondrion Localization
Pathways		RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
Drugs			Fostamatinib
Diseases
GWAS		Refractive error ( 32231278)	Bipolar disorder ( 22205951) Breast size ( 27182965) Fat distribution (HIV) ( 21897333)
Interacting Genes		30 interacting genes: ANP32B CAVIN1 CD300LF DNAAF6 EAF1 GABPB1 IFT57 INO80B LGALS7 LGALS7B MAPRE3 MARK1 MYC MYCN NEDD8 NUTF2 PCDH17 POLR3GL PPP1R11 PTEN RING1 SETBP1 SPANXN2 SPANXN3 TBK1 TLK1 UBC XAGE1B YY1 ZFP42	16 interacting genes: CCDC102B CCR6 ESRRG GJA5 INCA1 KCNK2 MAP2 MAP4 MAPT NIBAN1 STK11 TAOK1 TCL1B TGFB2 USH2A YAF2
Entrez ID		10138	4139
HPRD ID		09606	07353
Ensembl ID		ENSG00000015153	ENSG00000116141
Uniprot IDs		B4DJQ9 G3V212 Q8IY57	A0A087X0I6 A0A7I2YQC1 B4DIB3 Q9P0L2 X5D2M4
PDB IDs		2D9G	2HAK 3OSE 6C9D
Enriched GO Terms of Interacting Partners?
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