SACM1L and COPB2

Number of citations of the paper that reports this interaction (PubMedID 14527956)
46

Data Source:
HPRD (in vivo)

		SACM1L	COPB2
Description		SAC1 like phosphatidylinositide phosphatase	COPI coat complex subunit beta 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Endoplasmic Reticulum Membrane Endoplasmic Reticulum-plasma Membrane Contact Site	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol COPI Vesicle Coat Transport Vesicle
	Molecular Function	Phosphatidylinositol-3-phosphatase Activity Protein Binding Phosphatase Activity Phosphatidylinositol Bisphosphate Phosphatase Activity Phosphatidylinositol Phosphate 4-phosphatase Activity Phosphatidylinositol-4-phosphate Phosphatase Activity	Structural Molecule Activity Protein Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Phosphatidylinositol Dephosphorylation	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Toxin Transport
Pathways		Synthesis of PIPs at the ER membrane Synthesis of PIPs at the Golgi membrane	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Macular telangiectasia type 2 ( 33654266) Response to anti-depressant treatment in major depressive disorder ( 22041458) Serum metabolite levels ( 33031748) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Kawasaki disease ( 22446961) Male-pattern baldness ( 29146897)
Interacting Genes		35 interacting genes: ACKR2 AQP6 ARL13B CD79A COPA COPB2 COPG1 CREB3 CREB3L1 DHRS7 EBP FFAR2 FMO3 GPR151 GPR152 HSD17B13 JAGN1 LMNA MFF MFSD14B MTERF2 ODF4 PRKCA RNF19B RTN3 SCN3B SLC10A1 SLC10A6 SLC35A5 SLC35C2 SLC7A1 TMEM167B TMX2 VEZT ZFYVE27	15 interacting genes: ARCN1 COPA COPE MCPH1 MFHAS1 MSRA NDRG1 NFKB1 PRKCE RGS2 RGS4 SACM1L SUMO2 TMED10 WBP2
Entrez ID		22908	9276
HPRD ID		07587	06103
Ensembl ID		ENSG00000211456	ENSG00000184432
Uniprot IDs		B4DVV3 E9PGZ4 Q9NTJ5	P35606
PDB IDs
Enriched GO Terms of Interacting Partners?
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