DHX30 and OAS3

Number of citations of the paper that reports this interaction (PubMedID 21903422)
143

Data Source:
BioGRID (affinity chromatography technology, pull down)

		DHX30	OAS3
Description		DExH-box helicase 30	2'-5'-oligoadenylate synthetase 3
Image
GO Annotations	Cellular Component	Intracellular Anatomical Structure Cytoplasm Mitochondrion Cytosol Ribonucleoprotein Granule Mitochondrial Nucleoid	Extracellular Space Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Chromatin Binding RNA Binding RNA Helicase Activity Double-stranded RNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity	2'-5'-oligoadenylate Synthetase Activity Double-stranded RNA Binding Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Central Nervous System Development Mitochondrial Large Ribosomal Subunit Assembly	Nucleobase-containing Compound Metabolic Process Response To Virus Positive Regulation Of Interferon-beta Production Positive Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Chemokine (C-X-C Motif) Ligand 9 Production RIG-I Signaling Pathway MDA-5 Signaling Pathway Defense Response To Bacterium Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Negative Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Ribonuclease Activity Positive Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of Chemokine (C-C Motif) Ligand 5 Production Negative Regulation Of IP-10 Production Negative Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production
Pathways			Interferon gamma signaling OAS antiviral response Interferon alpha/beta signaling
Drugs
Diseases
GWAS			Alcohol consumption ( 21270382) Alcohol consumption (drinkers vs non-drinkers) ( 28485404) Body mass index ( 26426971) Chronic lymphocytic leukemia ( 28165464) HDL cholesterol ( 21909109) High density lipoprotein cholesterol levels ( 30718733) Hypertension ( 32709000) Low HDL-cholesterol levels ( 31006500) Myocardial infarction ( 30226566) Response to fenofibrate (adiponectin levels) ( 23149075) Right-sided colonic diverticulosis ( 31089239)
Interacting Genes		19 interacting genes: CDK9 DHX58 DUX4 HDAC1 HDAC3 HNRNPD MYBBP1A NCOR1 NEDD4 NR2E3 OAS3 OGT RBBP4 RBBP7 RBL1 SCAP SIN3A SKIL TBL3	5 interacting genes: DHX30 EIF6 FTSJ3 IFRD2 MAVS
Entrez ID		22907	4940
HPRD ID		13142	04519
Ensembl ID		ENSG00000132153	ENSG00000111331
Uniprot IDs		H7BXY3 Q7L2E3	Q9Y6K5
PDB IDs		2DB2	4S3N
Enriched GO Terms of Interacting Partners?
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