OAS3

Description		2'-5'-oligoadenylate synthetase 3
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GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	2'-5'-oligoadenylate Synthetase Activity Double-stranded RNA Binding Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Response To Virus Positive Regulation Of Interferon-beta Production Positive Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Chemokine (C-X-C Motif) Ligand 9 Production RIG-I Signaling Pathway MDA-5 Signaling Pathway Defense Response To Bacterium Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Negative Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Ribonuclease Activity Positive Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of Chemokine (C-C Motif) Ligand 5 Production Negative Regulation Of IP-10 Production Negative Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production
Pathways		Interferon gamma signaling OAS antiviral response Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Alcohol consumption ( 21270382) Alcohol consumption (drinkers vs non-drinkers) ( 28485404) Body mass index ( 26426971) Chronic lymphocytic leukemia ( 28165464) HDL cholesterol ( 21909109) High density lipoprotein cholesterol levels ( 30718733) Hypertension ( 32709000) Low HDL-cholesterol levels ( 31006500) Myocardial infarction ( 30226566) Response to fenofibrate (adiponectin levels) ( 23149075) Right-sided colonic diverticulosis ( 31089239)
Interacting Genes		5 interacting genes: DHX30 EIF6 FTSJ3 IFRD2 MAVS
Entrez ID		4940
HPRD ID		04519
Ensembl ID		ENSG00000111331
Uniprot IDs		Q9Y6K5
PDB IDs		4S3N
Enriched GO Terms of Interacting Partners?
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