FKBP4 and AHSA1

Number of citations of the paper that reports this interaction (PubMedID 25036637)
154

Data Source:
BioGRID (pull down, affinity chromatography technology, affinity chromatography technology)

		FKBP4	AHSA1
Description		FKBP prolyl isomerase 4	activator of HSP90 ATPase activity 1
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Cytosol Microtubule Protein-containing Complex Neuronal Cell Body Axonal Growth Cone Perinuclear Region Of Cytoplasm Extracellular Exosome	Endoplasmic Reticulum Cytosol Extracellular Exosome
	Molecular Function	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Protein-macromolecule Adaptor Activity Heat Shock Protein Binding Copper-dependent Protein Binding Tau Protein Binding	ATPase Activator Activity Protein Binding Cadherin Binding Chaperone Binding Hsp90 Protein Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Protein Folding Copper Ion Transport Negative Regulation Of Neuron Projection Development Negative Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Microtubule Polymerization Chaperone-mediated Protein Folding	Protein Folding Positive Regulation Of ATPase Activity Regulation Of Catalytic Activity
Pathways		HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Attenuation phase ESR-mediated signaling Estrogen-dependent gene expression Potential therapeutics for SARS
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Estradiol levels ( 34255042) FEV1 ( 30804560) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560) Quantitative traits ( 19197348) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		28 interacting genes: ACVR1 AHSA1 ATOX1 CALM1 CSNK2A1 EGFR ESR1 FES FKBP1A GLMN HSF1 HSP90AA1 HSPA4 IL2RA IRF4 NR3C1 NR3C2 OGT PHYH PTPN2 S100A1 S100A2 S100A6 SH3BP4 SMURF2 SNCA SQSTM1 STIP1	9 interacting genes: AKT1 APP CLCN1 EGFR FKBP4 GCH1 HSP90AA1 OGT PTGES3
Entrez ID		2288	10598
HPRD ID		11794	09768
Ensembl ID		ENSG00000004478	ENSG00000100591
Uniprot IDs		Q02790	G3V438 O95433
PDB IDs		1N1A 1P5Q 1Q1C 1QZ2 4DRJ 4LAV 4LAW 4LAX 4LAY 4TW8 6RCY	1X53
Enriched GO Terms of Interacting Partners?
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