AHSA1 and FKBP4

Number of citations of the paper that reports this interaction (PubMedID 25036637)
154

Data Source:
BioGRID (pull down, affinity chromatography technology, affinity chromatography technology)

		AHSA1	FKBP4
Description		activator of HSP90 ATPase activity 1	FKBP prolyl isomerase 4
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GO Annotations	Cellular Component	Endoplasmic Reticulum Cytosol Extracellular Exosome	Nucleoplasm Cytoplasm Mitochondrion Cytosol Microtubule Protein-containing Complex Neuronal Cell Body Axonal Growth Cone Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	ATPase Activator Activity Protein Binding Cadherin Binding Chaperone Binding Hsp90 Protein Binding	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Protein-macromolecule Adaptor Activity Heat Shock Protein Binding Copper-dependent Protein Binding Tau Protein Binding
	Biological Process	Protein Folding Positive Regulation Of ATPase Activity Regulation Of Catalytic Activity	Protein Peptidyl-prolyl Isomerization Protein Folding Copper Ion Transport Negative Regulation Of Neuron Projection Development Negative Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Microtubule Polymerization Chaperone-mediated Protein Folding
Pathways			HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Attenuation phase ESR-mediated signaling Estrogen-dependent gene expression Potential therapeutics for SARS
Drugs
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) Estradiol levels ( 34255042) FEV1 ( 30804560) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560) Quantitative traits ( 19197348) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		9 interacting genes: AKT1 APP CLCN1 EGFR FKBP4 GCH1 HSP90AA1 OGT PTGES3	28 interacting genes: ACVR1 AHSA1 ATOX1 CALM1 CSNK2A1 EGFR ESR1 FES FKBP1A GLMN HSF1 HSP90AA1 HSPA4 IL2RA IRF4 NR3C1 NR3C2 OGT PHYH PTPN2 S100A1 S100A2 S100A6 SH3BP4 SMURF2 SNCA SQSTM1 STIP1
Entrez ID		10598	2288
HPRD ID		09768	11794
Ensembl ID		ENSG00000100591	ENSG00000004478
Uniprot IDs		G3V438 O95433	Q02790
PDB IDs		1X53	1N1A 1P5Q 1Q1C 1QZ2 4DRJ 4LAV 4LAW 4LAX 4LAY 4TW8 6RCY
Enriched GO Terms of Interacting Partners?
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