RRAS2 and LGALS4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RRAS2	LGALS4
Description		RAS related 2	galectin 4
Image
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Plasma Membrane Focal Adhesion Membrane Extracellular Exosome	Cytosol Plasma Membrane Collagen-containing Extracellular Matrix
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Protein Binding Carbohydrate Binding
	Biological Process	Osteoblast Differentiation Ras Protein Signal Transduction Positive Regulation Of Cell Migration Regulation Of Neuron Death	Cell Adhesion
Pathways		RND1 GTPase cycle
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Apolipoprotein A1 levels ( 32203549) Brain morphology (MOSTest) ( 32665545) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Mitochondrial DNA levels ( 25240745) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Multiple sclerosis ( 31604244) Refractive error ( 32231278) Vitamin D levels ( 25208829) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Blood protein levels ( 30072576) Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
Interacting Genes		32 interacting genes: ACVR1 AFDN AHSG ARAF ARHGEF2 BMPR1B CREB3 FNTB HDAC7 LGALS4 PAWR PGGT1B PIK3R1 PTPN1 RABAC1 RAF1 RALGDS RAP1GDS1 RAPGEF1 RAPGEF3 RAPGEF4 RASGRF1 RASIP1 RASSF5 RGL3 RIN1 SMAD3 SMAD4 SMURF2 TRAF2 TRAF3 XRCC6	16 interacting genes: ARPC3 BANP CEP55 EYA2 GOLGA6L9 HOMEZ HOXA1 HSF2BP KIAA1549 KRTAP11-1 MLH1 NCKIPSD RFX6 RRAS2 TENM4 TOX2
Entrez ID		22800	3960
HPRD ID		02518	03949
Ensembl ID		ENSG00000133818	ENSG00000171747
Uniprot IDs		P62070	P56470 Q6FHZ4
PDB IDs		2ERY	1X50 4XZP 4YLZ 4YM0 4YM1 4YM2 4YM3 5CBL 5DUU 5DUV 5DUW 5DUX
Enriched GO Terms of Interacting Partners?
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