FGFR1 and RPS6KA3

  • Number of citations of the paper that reports this interaction (PubMedID 24141780)
  • 11
  • Data Source:
  • BioGRID (enzymatic study)

FGFR1

RPS6KA3

Description fibroblast growth factor receptor 1 ribosomal protein S6 kinase A3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Age at first sexual intercourse ( 34211149)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Bipolar disorder ( 31043756)
  • Birth weight ( 31043758)
  • Body size at age 10 ( 32376654)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Erosive tooth wear (severe vs non-severe) ( 29898447)
  • Erosive tooth wear (severe vs none or mild) ( 29898447)
  • Nonsyndromic cleft lip with cleft palate ( 28232668)
  • PR interval ( 30046033 32439900)
  • Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
  • Schizophrenia ( 29483656)
  • Triglyceride levels ( 32203549)
  • Type 2 diabetes ( 32499647)
Interacting Genes 74 interacting genes: BNIP2 CDH1 CREBBP CRK CTPS2 EIF4EBP1 EPHA4 ERBB2 ERBB3 FBXO7 FDPS FGF1 FGF10 FGF17 FGF18 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FLRT3 FRS2 FRS3 GRB14 GRB2 HTR1A HULC IL17RD ITGB3 ITK KLB KPNB1 L1CAM LDHA MFHAS1 MMP2 NCAM1 NCK1 NCK2 NECTIN1 NEDD4 NRG1 NRP1 OR51B4 PDGFRB PDK1 PDP1 PIK3R1 PIK3R2 PKM PLCG1 PPP2CB PTK6 PTPN1 RARA RASA1 RPS6KA1 RPS6KA3 RTN1 RTN3 SH3BP2 SHB SHC1 SLA SOS1 TNK2 TNS2 TPMT VAV1 YES1 ZFYVE1 41 interacting genes: ATP5PF BAD BARX1 CREB1 CREBBP CTNND1 DPYD EIF3C ESR1 FBXO7 FGF2 FGFR1 FGFR3 FYN GRIN1 GRIN2D H2AX H3-4 H3C1 HMGN1 HMGN2 HTR2A ILKAP KRT18 MAGI1 MAPK1 MAPK3 MAPT MASP1 NEDD4 NFKBIA NR4A1 PDPK1 PEA15 SHANK1 SMS SRC STK11 SUMO2 TP53 YBX1
Entrez ID 2260 6197
HPRD ID 00634 02092
Ensembl ID ENSG00000077782 ENSG00000177189
Uniprot IDs A0A0S2Z3Q6 A0A3B3ISD1 P11362 A0A384MDW3 B1AXG1 B4DG22 B7ZB17 P51812
PDB IDs 1AGW 1CVS 1EVT 1FGI 1FGK 1FQ9 1XR0 2CR3 2FGI 3C4F 3DPK 3GQI 3GQL 3JS2 3KRJ 3KRL 3KXX 3KY2 3OJV 3RHX 3TT0 4F63 4F64 4F65 4NK9 4NKA 4NKS 4RWI 4RWJ 4RWK 4RWL 4UWB 4UWC 4UWY 4V01 4V04 4V05 4WUN 4ZSA 5A46 5A4C 5AM6 5AM7 5B7V 5EW8 5FLF 5O49 5O4A 5UQ0 5UR1 5VND 5W21 5W59 5Z0S 5ZV2 6C18 6C19 6C1B 6C1C 6C1O 6ITJ 6MZQ 6MZW 6NVL 6P68 6P69 4D9T 4D9U 4JG6 4JG7 4JG8 4NUS 4NW5 4NW6 5D9K 5D9L
Enriched GO Terms of Interacting Partners?
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