FGFR1 and KPNB1

  • Number of citations of the paper that reports this interaction (PubMedID 11257130)
  • 84
  • Data Source:
  • HPRD (in vivo)

FGFR1

KPNB1

Description fibroblast growth factor receptor 1 karyopherin subunit beta 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Age at first sexual intercourse ( 34211149)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Bipolar disorder ( 31043756)
  • Birth weight ( 31043758)
  • Body size at age 10 ( 32376654)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Erosive tooth wear (severe vs non-severe) ( 29898447)
  • Erosive tooth wear (severe vs none or mild) ( 29898447)
  • Nonsyndromic cleft lip with cleft palate ( 28232668)
  • PR interval ( 30046033 32439900)
  • Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
  • Schizophrenia ( 29483656)
  • Triglyceride levels ( 32203549)
  • Type 2 diabetes ( 32499647)
  • Asthma ( 31619474)
  • Body mass index ( 26426971)
  • Glycine levels ( 30837465)
  • HDL cholesterol ( 30275531)
  • HDL cholesterol levels ( 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Hip circumference adjusted for BMI ( 34021172)
  • LDL cholesterol levels ( 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Multiple sclerosis ( 22190364)
  • Optic cup area ( 25631615)
  • Simvastatin-induced myopathy ( 31220337)
  • Total cholesterol levels ( 33339817)
  • Triglyceride levels ( 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes 74 interacting genes: BNIP2 CDH1 CREBBP CRK CTPS2 EIF4EBP1 EPHA4 ERBB2 ERBB3 FBXO7 FDPS FGF1 FGF10 FGF17 FGF18 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FLRT3 FRS2 FRS3 GRB14 GRB2 HTR1A HULC IL17RD ITGB3 ITK KLB KPNB1 L1CAM LDHA MFHAS1 MMP2 NCAM1 NCK1 NCK2 NECTIN1 NEDD4 NRG1 NRP1 OR51B4 PDGFRB PDK1 PDP1 PIK3R1 PIK3R2 PKM PLCG1 PPP2CB PTK6 PTPN1 RARA RASA1 RPS6KA1 RPS6KA3 RTN1 RTN3 SH3BP2 SHB SHC1 SLA SOS1 TNK2 TNS2 TPMT VAV1 YES1 ZFYVE1 69 interacting genes: AMFR CD99 CHD3 CRBN CSE1L CSNK1A1 CUL4B ELAVL1 EPAS1 EXO1 FGFR1 H1-0 H1-2 IGFBP3 IGFBP5 IPO7 IPO8 ITCH KPNA1 KPNA2 KPNA3 KPNA4 KPNA6 LINC01554 LYST MESD MSL1 MTNR1A NFATC1 NFYA NUP153 NUP50 NUP54 NUP62 NUP98 NUTF2 OGT PIAS4 PLCD1 PRKD3 PTEN PTHLH PTMA PTN PTPN2 RAN RANBP1 RANBP2 RBX1 RPL5 RUNX1T1 SELENOS SENP2 SMAD2 SMAD3 SMN1 SMNDC1 SNAI1 SNAPIN SNUPN SOX9 SREBF2 SRY TAF3 TAF8 TERF1 TP53 TUBA1A UBR5
Entrez ID 2260 3837
HPRD ID 00634 04114
Ensembl ID ENSG00000077782 ENSG00000108424
Uniprot IDs A0A0S2Z3Q6 A0A3B3ISD1 P11362 B7Z752 Q14974
PDB IDs 1AGW 1CVS 1EVT 1FGI 1FGK 1FQ9 1XR0 2CR3 2FGI 3C4F 3DPK 3GQI 3GQL 3JS2 3KRJ 3KRL 3KXX 3KY2 3OJV 3RHX 3TT0 4F63 4F64 4F65 4NK9 4NKA 4NKS 4RWI 4RWJ 4RWK 4RWL 4UWB 4UWC 4UWY 4V01 4V04 4V05 4WUN 4ZSA 5A46 5A4C 5AM6 5AM7 5B7V 5EW8 5FLF 5O49 5O4A 5UQ0 5UR1 5VND 5W21 5W59 5Z0S 5ZV2 6C18 6C19 6C1B 6C1C 6C1O 6ITJ 6MZQ 6MZW 6NVL 6P68 6P69 1F59 1IBR 1M5N 1O6O 1O6P 1QGK 1QGR 2P8Q 2Q5D 2QNA 3LWW 3W5K 6N88 6N89
Enriched GO Terms of Interacting Partners?
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