FGF12 and DCTD

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		FGF12	DCTD
Description		fibroblast growth factor 12	dCMP deaminase
Image
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Synapse	Cytosol
	Molecular Function	Protein Binding Growth Factor Activity Sodium Channel Regulator Activity Transmembrane Transporter Binding	DCMP Deaminase Activity Protein Binding Zinc Ion Binding Identical Protein Binding
	Biological Process	Regulation Of Membrane Depolarization Signal Transduction Cell-cell Signaling Chemical Synaptic Transmission Nervous System Development Heart Development Adult Locomotory Behavior Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Sodium Ion Transport Neuromuscular Process Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Neuronal Action Potential Regulation Of Sodium Ion Transmembrane Transport Regulation Of Voltage-gated Sodium Channel Activity Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Cation Channel Activity	Pyrimidine Nucleotide Metabolic Process DUMP Biosynthetic Process DTMP Biosynthetic Process
Pathways		Phase 0 - rapid depolarisation	Interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Bipolar disorder ( 31043756) Fasting glucose ( 34059833) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) HDL cholesterol levels in HIV infection ( 33109212) Height ( 32902719) Hip circumference adjusted for BMI ( 28552196) Idiopathic dilated cardiomyopathy ( 29495422) Ileal carcinoids ( 21139019) Major depressive disorder ( 23377640) Metabolite levels ( 19043545) Orofacial cleft x maternal periconceptional smoking interaction (1df) ( 33937227) Post bronchodilator FEV1/FVC ratio ( 26634245) PR interval ( 32439900) Serum metabolite concentrations in chronic kidney disease ( 29545352) Severe influenza A (H1N1) infection ( 26379185) Sleep quality ( 23728906)	Diisocyanate-induced asthma ( 25918132) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Wegener's granulomatosis ( 23740775)
Interacting Genes		27 interacting genes: AP2M1 APP COIL CT45A1 DACH1 DCTD DPPA2 GRIP1 IKZF1 IL2RA LZTS2 MAPK13 MAPK8IP2 NEDD4 NEDD4L PJA1 RBAK RNF151 RP9 SMURF1 SRPK1 SRPK2 STAC3 THAP1 YWHAE ZNF460 ZNF79	15 interacting genes: CEP76 CTLA4 FGF12 FXR1 FXR2 GORASP2 LNX1 MALSU1 NIF3L1 NUDT18 PICK1 PSMA1 SDCBP TXN2 UBE2I
Entrez ID		2257	1635
HPRD ID		03303	09623
Ensembl ID		ENSG00000114279	ENSG00000129187
Uniprot IDs		P61328	P32321
PDB IDs		1Q1U 4JQ0	2W4L
Enriched GO Terms of Interacting Partners?
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