FES and IRS1

  • Number of citations of the paper that reports this interaction (PubMedID 10856136)
  • 94
  • Data Source:
  • HPRD (in vitro)

FES

IRS1

Description FES proto-oncogene, tyrosine kinase insulin receptor substrate 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 50 interacting genes: ALDH1B1 APP AR BCAR1 BCR BLM CBX5 CSF2RB DOK1 DPYSL5 EGFR ERBB2 ERBB3 ERBB4 FKBP4 FKBP5 FURIN GAB1 HSH2D HSPA4 IL4R IRS1 IRS2 JAK1 JAK2 JAK3 KIT MAN2A2 MDFI MET NEDD4 NLGN4X PDE4DIP PEX11A PIK3R1 PLXNA1 POT1 PPID PTGES3 RASA1 RASA3 SMURF1 STARD5 STAT3 TERF1 TRIM28 VANGL1 ZNF117 ZNF746 ZNF775 81 interacting genes: AKT1 ALK AP3S1 APP ATP2A1 ATP2A2 ATP2A3 BCL2L1 BCR CAV1 CDH1 CHUK CRK CSNK2A1 CSNK2B EGFR ERBB2 FBXO25 FBXW8 FER FES FYN GHR GRB10 GRB14 GRB2 IGF1R IKBKB IL4R INSR JAK1 JAK2 JAK3 MAPK1 MAPK3 MAPK8 MAPK9 MTOR NCK2 NEDD4 NPM1 NRDC NTRK1 NUMB PASK PDPK1 PELI1 PHIP PIK3R1 PIK3R2 PIK3R3 PLCG2 PRKCD PRKCG PRKCQ PRKCZ PTK2 PTPN1 PTPN11 PTPRC PTPRD PTPRF PTPRU RAD51 ROCK1 RPS6KB1 RPTOR SHC1 SIK2 SOCS1 SOCS3 TERT TRIM72 TUB TYK2 UBC UBTF YWHAB YWHAE YWHAG YWHAZ
Entrez ID 2242 3667
HPRD ID 01814 00943
Ensembl ID ENSG00000182511 ENSG00000169047
Uniprot IDs A0A024RC92 P07332 P35568
PDB IDs 1WQU 2DCR 3BKB 3CBL 3CD3 4DYL 4E93 6JMF 1IRS 1K3A 1QQG 2Z8C 5U1M 6BNT
Enriched GO Terms of Interacting Partners?
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