ALDH3A2 and COL6A1

		ALDH3A2	COL6A1
Description		aldehyde dehydrogenase 3 family member A2	collagen type VI alpha 1 chain
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Peroxisomal Membrane Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Extracellular Region Collagen Type VI Trimer Extracellular Space Lysosomal Membrane Endoplasmic Reticulum Lumen Membrane Protein-containing Complex Sarcolemma Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Aldehyde Dehydrogenase (NAD+) Activity Protein Binding Protein Homodimerization Activity Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (non-phosphorylating) Activity Long-chain-alcohol Oxidase Activity Long-chain-aldehyde Dehydrogenase Activity Medium-chain-aldehyde Dehydrogenase Activity	Collagen Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength Platelet-derived Growth Factor Binding
	Biological Process	Cellular Aldehyde Metabolic Process Fatty Acid Metabolic Process Central Nervous System Development Peripheral Nervous System Development Epidermis Development Phytol Metabolic Process Hexadecanal Metabolic Process	Osteoblast Differentiation Cell Adhesion Endodermal Cell Differentiation Cellular Response To Amino Acid Stimulus
Pathways		RND2 GTPase cycle RND1 GTPase cycle	Collagen degradation Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions ECM proteoglycans ECM proteoglycans NCAM1 interactions Collagen chain trimerization
Drugs		NADH
Diseases
GWAS			Blood protein levels ( 30072576 29875488) Bone mineral density (lumbar spine) in inflammatory bowel disease ( 29603369) Corneal hysteresis ( 32716492 30894546) Corneal resistance factor ( 31246245 32716492 30894546) Daytime nap ( 33568662) Diverticular disease ( 30177863) Intraocular pressure ( 29617998 29235454) Keratoconus ( 33649486) Myopia ( 27182965) Pulse pressure ( 30224653 30578418) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure ( 28234671) Waist circumference adjusted for body mass index ( 34021172 25673412)
Interacting Genes		2 interacting genes: COL6A1 DISC1	24 interacting genes: ALDH3A2 CFAP410 COL2A1 COL6A2 CSTB DCN DNAJB11 FAM3B FGF7 HCFC2 LAMB1 LCMT2 LGALS3BP MAG MLLT3 MPRIP MTDH PCNT PDGFA PDGFB PDK1 PEX26 PIGS RUNX1
Entrez ID		224	1291
HPRD ID		07188	00370
Ensembl ID		ENSG00000072210	ENSG00000142156
Uniprot IDs		P51648	A0A384P5H7 P12109
PDB IDs		4QGK
Enriched GO Terms of Interacting Partners?
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