FDX1 and CNTN5

		FDX1	CNTN5
Description		ferredoxin 1	contactin 5
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Extracellular Region Plasma Membrane GABA-ergic Synapse Anchored Component Of Presynaptic Membrane
	Molecular Function	Iron Ion Binding Electron Transfer Activity 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Steroid Biosynthetic Process Cholesterol Metabolic Process Electron Transport Chain Hormone Biosynthetic Process Cellular Response To CAMP Cellular Response To Forskolin	Cell Adhesion Sensory Perception Of Sound Presynapse Assembly
Pathways		Mitochondrial iron-sulfur cluster biogenesis Pregnenolone biosynthesis Endogenous sterols Electron transport from NADPH to Ferredoxin Defective CYP11A1 causes AICSR	Post-translational modification: synthesis of GPI-anchored proteins
Drugs		Mitotane
Diseases
GWAS		Cognitive function ( 24684796) Coronary artery disease ( 32469254) Serum metabolite levels ( 33031748)	Alcohol dependence ( 26365420) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Asthma ( 29273806) Atrial fibrillation ( 17903304) Behcet's disease ( 27548383) Bipolar disorder and schizophrenia ( 20889312) Blood protein levels ( 30072576 29875488 28240269) Bone mineral density (femoral neck) ( 26911590) Cardiorespiratory fitness (800m run time) ( 32572135) Carotid intima media thickness x smoking interaction ( 32117412) Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Chronotype ( 30696823) Diastolic blood pressure ( 27841878) Factor VII activity ( 30642921) Feeling miserable ( 29500382) Fructosamine levels ( 29844224) Glycated hemoglobin levels ( 28898252) Gout vs. Hyperuricemia ( 31289104) HDL cholesterol levels in HIV infection ( 33109212) Immune reponse to smallpox (secreted IL-2) ( 22610502) Loneliness (multivariate analysis) ( 27629369) Major depressive disorder x sex interaction ( 34099189) Myopia (pathological) ( 23049088) Neurological blood protein biomarker levels ( 31320639) Obesity-related traits ( 23251661) Objective response to lithium treatment in bipolar disorder ( 26503763) Plasma kynurenine levels in major depressive disorder ( 29317604) Spatial memory ( 31596458) Total glycated albumin levels ( 29844224) Volumetric brain MRI ( 17903297) Waist-hip ratio ( 25673412)
Interacting Genes		12 interacting genes: BIRC2 BIRC3 CNTN5 CORO2A CYCS CYP11A1 CYP11B2 FDXR LILRB2 PBRM1 PRKAB2 RDH5	2 interacting genes: FDX1 VRK2
Entrez ID		2230	53942
HPRD ID		00059	06241
Ensembl ID		ENSG00000137714	ENSG00000149972
Uniprot IDs		P10109	O94779
PDB IDs		3N9Y 3N9Z 3NA0 3NA1 3P1M	4N68 5E52
Enriched GO Terms of Interacting Partners?
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