BEND7 and PRMT3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		BEND7	PRMT3
Description		BEN domain containing 7	protein arginine methyltransferase 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Exosome	Cytoplasm Cytosol
	Molecular Function	DNA Binding Protein Binding	Protein Binding Methyltransferase Activity Protein-arginine N-methyltransferase Activity Ribosome Binding Metal Ion Binding
	Biological Process		Protein Methylation Negative Regulation Of Protein Ubiquitination Peptidyl-arginine N-methylation Negative Regulation Of Retinoic Acid Biosynthetic Process
Pathways			RMTs methylate histone arginines Protein methylation
Drugs			S-adenosyl-L-homocysteine
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Diastolic blood pressure ( 30224653) Free thyroxine concentration ( 30367059) Hematocrit ( 32888494) Hemoglobin ( 32888494) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) PR interval ( 32439900) Schizophrenia x sex interaction ( 34099189) Skin pigmentation ( 28300201) Smoking status (ever vs never smokers) ( 30643258) White blood cell count ( 32888494)	Carotid intima media thickness (maximum) ( 31801372) Number of alcoholic drinks required to feel an effect (long-term average) ( 31270906) Pursuit maintenance gain ( 29064472) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)
Interacting Genes		75 interacting genes: ANP32B BANF2 BYSL C14orf119 CDC37 CDCA7L CEP44 CHD2 CIB3 CSNK2A1 DDX6 DVL2 DVL3 EAF1 EAF2 EIF1AD EMD FAM124A FAM133A GADD45G GEMIN2 GTPBP3 GYS1 HMBOX1 HSF2BP KANK2 L3MBTL2 LMO3 LNX1 LYAR MAGOHB MBD2 MFAP1 MLX MORF4L1 MORF4L2 MYO15B NAP1L3 NEK6 NIF3L1 NKAPD1 NOL12 NUTF2 OGT OSGIN1 PBLD PIM1 PLEKHF2 POLR3GL PPIG PPP1R37 PRMT3 PRPF40A PSMB1 PSMF1 RAB29 RBM10 RIPPLY1 RPL22 SCNM1 SDCBP SDCBP2 SMARCA2 SPANXN2 THAP1 TLK1 TNPO2 TRIM26 U2AF2 UBL5 USP20 VCX2 WHRN ZCCHC10 ZNF622	10 interacting genes: BEND7 FBL HNRNPA1 MEOX2 PABPN1 PIH1D2 PPARD RASSF2 STAT1 TSC22D2
Entrez ID		222389	10196
HPRD ID		12570	11934
Ensembl ID		ENSG00000165626	ENSG00000185238
Uniprot IDs		Q8N7W2	O60678 Q8WUV3
PDB IDs			2FYT 3SMQ 4HSG 4QQN 4RYL
Enriched GO Terms of Interacting Partners?
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