PRMT3 and FBL

Number of citations of the paper that reports this interaction (PubMedID 16157300)
22

Data Source:
BioGRID (enzymatic study)

		PRMT3	FBL
Description		protein arginine methyltransferase 3	fibrillarin
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol	Fibrillar Center Dense Fibrillar Component Granular Component Nucleus Nucleoplasm Chromosome Nucleolus Cajal Body Membrane Box C/D RNP Complex Small-subunit Processome Extracellular Exosome
	Molecular Function	Protein Binding Methyltransferase Activity Protein-arginine N-methyltransferase Activity Ribosome Binding Metal Ion Binding	TFIID-class Transcription Factor Complex Binding RNA Binding Protein Binding RRNA Methyltransferase Activity ATPase Binding Histone-glutamine Methyltransferase Activity
	Biological Process	Protein Methylation Negative Regulation Of Protein Ubiquitination Peptidyl-arginine N-methylation Negative Regulation Of Retinoic Acid Biosynthetic Process	Box C/D RNA 3'-end Processing Osteoblast Differentiation RRNA Processing RRNA Methylation SnoRNA Localization Histone Glutamine Methylation
Pathways		RMTs methylate histone arginines Protein methylation	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs		S-adenosyl-L-homocysteine
Diseases
GWAS		Carotid intima media thickness (maximum) ( 31801372) Number of alcoholic drinks required to feel an effect (long-term average) ( 31270906) Pursuit maintenance gain ( 29064472) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)
Interacting Genes		10 interacting genes: BEND7 FBL HNRNPA1 MEOX2 PABPN1 PIH1D2 PPARD RASSF2 STAT1 TSC22D2	21 interacting genes: DDX17 DDX5 ERG H2AC20 KLF6 MAP3K14 PIN4 PRMT1 PRMT3 PRMT6 PRMT8 PSMB6 PTEN RUVBL1 RUVBL2 SMN1 SMN2 SNRPN TAF9 TBC1D17 ZNF792
Entrez ID		10196	2091
HPRD ID		11934	00617
Ensembl ID		ENSG00000185238	ENSG00000105202
Uniprot IDs		O60678 Q8WUV3	P22087
PDB IDs		2FYT 3SMQ 4HSG 4QQN 4RYL	2IPX
Enriched GO Terms of Interacting Partners?
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