FCER1A and MESD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FCER1A	MESD
Description		Fc fragment of IgE receptor Ia	mesoderm development LRP chaperone
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface	Endoplasmic Reticulum Plasma Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding IgE Binding	Molecular_function Protein Binding Identical Protein Binding Low-density Lipoprotein Particle Receptor Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Regulation Of Immune Response	Ossification Protein Folding Phagocytosis Mesoderm Development Wnt Signaling Pathway Protein Localization To Cell Surface Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering
Pathways		Fc epsilon receptor (FCERI) signaling Fc epsilon receptor (FCERI) signaling Role of LAT2/NTAL/LAB on calcium mobilization Role of LAT2/NTAL/LAB on calcium mobilization FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization FCERI mediated NF-kB activation
Drugs		Omalizumab Benzylpenicilloyl polylysine TNX-901
Diseases
GWAS		C-reactive protein ( 22939635) IgE levels ( 18846228 22075330) Obesity-related traits ( 23251661) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Select biomarker traits ( 17903293) White blood cell count ( 27863252)
Interacting Genes		7 interacting genes: FCER1G FCGR2A ITIH2 LMNA MESD MS4A2 PDHB	75 interacting genes: - ABCG8 ABITRAM ACBD7 ADAL AKIRIN2 AKNAD1 AKT1 APP ASH2L ATP6V1E1 ATP6V1E2 BORCS8 BORCS8-MEF2B BRD4 C17orf75 CCDC105 CDR2L CENATAC CENPH CHCHD1 CLP1 CNOT9 COL10A1 COL1A2 COX14 COX5A CUTC CYP4F11 DDX6 ENKD1 FAM13C FAM172A FARS2 FCER1A GEM GOLGA7 GPKOW GTPBP3 H2AB2 H2AB3 HSBP1L1 IGF1 KPNB1 LCE1A LRP5 LY96 MAGEB4 MAP1LC3B MCM9 MELTF MKNK2 MRM1 MTNR1A NRDE2 PMF1 PSMA5 QARS1 RCOR3 RFC3 SMARCB1 SNX5 SNX7 TEX12 TEX48 TPM2 TREX2 TRMT2A TTC21A TTC23 TYMP UBQLN1 ZNF493 ZNF827 ZNF844
Entrez ID		2205	23184
HPRD ID		00917	12129
Ensembl ID		ENSG00000179639	ENSG00000117899
Uniprot IDs		P12319	Q14696
PDB IDs		1ALS 1ALT 1F2Q 1F6A 1J86 1J87 1J88 1J89 1RPQ 2Y7Q
Enriched GO Terms of Interacting Partners?
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