MTIF3 and HTATIP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MTIF3	HTATIP2
Description		mitochondrial translational initiation factor 3	HIV-1 Tat interactive protein 2
Image
GO Annotations	Cellular Component	Mitochondrion	Nucleus Nuclear Envelope Cytoplasm Cytosol Membrane
	Molecular Function	Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ribosome Binding Ribosomal Small Subunit Binding	Transcription Coactivator Activity Protein Serine/threonine Kinase Activity Protein Binding Oxidoreductase Activity
	Biological Process	Ribosome Disassembly Mitochondrial Translational Initiation	Angiogenesis Regulation Of Transcription By RNA Polymerase II Apoptotic Process Cell Differentiation Negative Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Angiogenesis Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation Import Into Nucleus
Pathways		Mitochondrial translation initiation
Drugs			Polyethylene glycol 400
Diseases
GWAS		Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) BMI x environmental factors (excluding physical activity) interaction ( 33654129) BMI x environmental factors (including physical activity) interaction ( 33654129) Body mass index ( 28892062 25673413 20935630) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Estimated glomerular filtration rate change in renal transplantation (recipient effect) ( 30920136) Night sleep phenotypes ( 27126917) Psychosis proneness (hypomanic personality scale and perceptual aberration scale) ( 28525603)	Bell's palsy ( 33602968) Fractional shortening ( 29403010) Obesity-related traits ( 23251661) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)
Interacting Genes		85 interacting genes: APOD BCL2L1 BMP10 BPIFA1 BRICD5 CABP7 CD47 CDIPT CDS2 CGRRF1 CLDND2 CLEC7A CMTM5 COL4A5 COQ8A CTXN3 CXCL9 CYBC1 CYP4F2 EPGN FBXO7 FETUB FXYD3 FXYD6-FXYD2 HSFX1 HSFX2 HTATIP2 ITGB2 JAGN1 LAPTM4B LAT LDLR LHFPL5 MAPK1 MGST3 MRFAP1 MS4A1 NAT8 NDRG4 ORMDL3 PAN3 PAXIP1 PEA15 PLN PLP1 PRH1 RPRM SCD SELENOK SERP1 SERP2 SERTM1 SIAH1 SNX2 SPANXN2 STARD4 STATH STRIT1 STX3 STX6 THBD THSD7B TMED8 TMEM109 TMEM11 TMEM128 TMEM147 TMEM176A TMEM218 TMEM239 TMEM242 TMEM243 TMEM254 TMEM42 TMEM97 TRARG1 TSPAN33 TUFM UNC50 VAMP4 VEZT VKORC1L1 YIPF6 ZDHHC15 ZNF202	25 interacting genes: ABHD4 ACSL4 AQP6 ASF1A EHHADH ETS1 FAM209A FITM2 GET1 HDAC6 HSD17B11 JAGN1 JPH1 MIEF1 MTIF3 NCOA5 PITPNC1 PLIN2 RAB5A REEP4 RETREG3 SH3GLB1 SLC10A6 TMEM115 TMX2
Entrez ID		219402	10553
HPRD ID		17609	09288
Ensembl ID		ENSG00000122033	ENSG00000109854
Uniprot IDs		Q9H2K0	Q9BUP3
PDB IDs		6NEQ 6NF8 6RW4 6RW5	2BKA
Enriched GO Terms of Interacting Partners?
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