MTIF3 and FXYD6-FXYD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MTIF3	FXYD6-FXYD2
Description		mitochondrial translational initiation factor 3	FXYD6-FXYD2 readthrough
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion
	Molecular Function	Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ribosome Binding Ribosomal Small Subunit Binding
	Biological Process	Ribosome Disassembly Mitochondrial Translational Initiation
Pathways		Mitochondrial translation initiation
Drugs
Diseases
GWAS		Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) BMI x environmental factors (excluding physical activity) interaction ( 33654129) BMI x environmental factors (including physical activity) interaction ( 33654129) Body mass index ( 28892062 25673413 20935630) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Estimated glomerular filtration rate change in renal transplantation (recipient effect) ( 30920136) Night sleep phenotypes ( 27126917) Psychosis proneness (hypomanic personality scale and perceptual aberration scale) ( 28525603)	Hippocampal volume in Alzheimer's disease dementia ( 29274321)
Interacting Genes		85 interacting genes: APOD BCL2L1 BMP10 BPIFA1 BRICD5 CABP7 CD47 CDIPT CDS2 CGRRF1 CLDND2 CLEC7A CMTM5 COL4A5 COQ8A CTXN3 CXCL9 CYBC1 CYP4F2 EPGN FBXO7 FETUB FXYD3 FXYD6-FXYD2 HSFX1 HSFX2 HTATIP2 ITGB2 JAGN1 LAPTM4B LAT LDLR LHFPL5 MAPK1 MGST3 MRFAP1 MS4A1 NAT8 NDRG4 ORMDL3 PAN3 PAXIP1 PEA15 PLN PLP1 PRH1 RPRM SCD SELENOK SERP1 SERP2 SERTM1 SIAH1 SNX2 SPANXN2 STARD4 STATH STRIT1 STX3 STX6 THBD THSD7B TMED8 TMEM109 TMEM11 TMEM128 TMEM147 TMEM176A TMEM218 TMEM239 TMEM242 TMEM243 TMEM254 TMEM42 TMEM97 TRARG1 TSPAN33 TUFM UNC50 VAMP4 VEZT VKORC1L1 YIPF6 ZDHHC15 ZNF202	33 interacting genes: APH1B APOL3 AQP6 AVPR2 BEST1 BNIP3 CERS4 CLDN5 FAM210B GPR152 GPR37L1 GPRC5D MTIF3 PGRMC2 RNF170 SLC10A1 SLC10A6 SLC16A13 SLC19A3 SLC2A13 SLC34A2 SLC35C2 SLC7A8 SPCS1 TLCD4 TMEM14B TMEM167B TMEM205 TMEM41A TMPPE TMX2 TRHR UNC93A
Entrez ID		219402	100533181
HPRD ID		17609
Ensembl ID		ENSG00000122033	ENSG00000255245
Uniprot IDs		Q9H2K0	A0A087WZ82 A0A0A6YYL5
PDB IDs		6NEQ 6NF8 6RW4 6RW5
Enriched GO Terms of Interacting Partners?
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