EXT1 and NOTCH1

  • Number of citations of the paper that reports this interaction (PubMedID 27229929)
  • 8
  • Data Source:
  • BioGRID (two hybrid)

EXT1

NOTCH1

Description exostosin glycosyltransferase 1 notch receptor 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Autism spectrum disorder ( 28540026)
  • Common carotid intima-media thickness ( 29206233)
  • Common carotid intima-media thickness in HIV infection ( 29206233)
  • Depression in smokers ( 30219690)
  • Endometrial cancer (Non-endometrioid histology) ( 30093612)
  • Facial attractiveness (female raters) ( 30946739)
  • General cognitive ability ( 29844566)
  • Height ( 19893584)
  • Household income (MTAG) ( 31844048)
  • Obesity-related traits ( 23251661)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Urate levels in obese individuals ( 25811787)
  • White blood cell count (basophil) ( 29403010)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Crohn's disease ( 28067908)
  • Eosinophil counts ( 32888494)
  • Inflammatory bowel disease ( 28067908)
  • Length of menstrual cycle ( 26732621)
  • Mean corpuscular hemoglobin ( 32888494)
  • Red cell distribution width ( 28957414)
  • Serum alkaline phosphatase levels ( 33547301)
  • Triglyceride levels ( 32203549)
  • Ulcerative colitis ( 28067908)
Interacting Genes 4 interacting genes: EXT2 FBXW7 NOTCH1 TRAP1 87 interacting genes: ADAM17 AKT1 APBA1 ARL6IP5 B3GALT4 BLOC1S1 CACNA1A CAMK4 CASR CBL CCN3 CEP57L1 CNTN1 COL4A6 CTNNB1 DAZAP2 DLL1 DLL4 DTX1 DTX2 EGFL7 EP300 EXT1 FAM185A FBP1 FBXW7 FURIN GFI1B GOLGA2 GOPC GSK3B HMGN5 HOXA1 ILK ITCH JAG1 JAG2 KAT2A KAT2B KIAA1191 LCK LEF1 LFNG LINC00260 LINC02907 LNX2 MAGEA1 MAGED1 MAML1 MAML2 MAML3 MAP3K1 MBD1 MDM2 MEF2C MFNG NFKB1 NUMB NUMBL PIK3CG POFUT1 POU2AF1 PRKCD PSEN1 PSEN2 RBP3 RBPJ REL RELA RHOA RUNX3 SHANK3 SMAD3 SNAI1 SNW1 STC1 TLE3 TOR1A USP10 USP12 USP2 USP7 WDR12 WWP1 XIAP XRCC6 YY1
Entrez ID 2131 4851
HPRD ID 00598 01827
Ensembl ID ENSG00000182197 ENSG00000148400
Uniprot IDs Q16394 P46531
PDB IDs 1PB5 1TOZ 1YYH 2F8X 2F8Y 2HE0 2VJ3 3ETO 3I08 3L95 3NBN 3V79 4CUD 4CUE 4CUF 4D0E 4D0F 5FM9 5FMA 5KZO 5L0R 5UB5 6IDF 6PY8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?