ETFDH and TRIM69

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ETFDH	TRIM69
Description		electron transfer flavoprotein dehydrogenase	tripartite motif containing 69
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Matrix Integral Component Of Mitochondrial Inner Membrane Mitochondrial Membrane	Nucleus Cytoplasm Cytosol Nuclear Speck
	Molecular Function	Electron-transferring-flavoprotein Dehydrogenase Activity Protein Binding Electron Transfer Activity Oxidoreductase Activity Metal Ion Binding Quinone Binding Ubiquinone Binding Flavin Adenine Dinucleotide Binding 4 Iron, 4 Sulfur Cluster Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Response To Oxidative Stress Electron Transport Chain Respiratory Electron Transport Chain Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase	Apoptotic Process Protein Ubiquitination
Pathways		Respiratory electron transport	Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Metformin 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
Diseases
GWAS		Acylcarnitine levels ( 26068415) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Blood protein levels ( 28240269) Metabolic traits ( 21886157) Metabolite levels ( 31628463 20037589) Serum metabolite levels ( 33031748 23093944)	Estimated glomerular filtration rate in non-diabetics ( 31451708)
Interacting Genes		9 interacting genes: CLCN3 GSC2 HSD17B10 KRTAP11-1 KRTAP13-2 MYH7B OTX1 TRIM69 ZNF581	53 interacting genes: AIFM2 APP ASNS ATP5MC1 BEX2 BIN3 C4orf45 CDSN DVL1 ETFDH FAM110A FAM161A FAM90A1 FKBP1B GEM HAUS1 HGS IYD KLHL38 KRT17 LARP1B LYSMD1 MAGEA4 MAJIN MED20 MID2 NEK8 NTAQ1 PML POLR3K PPP1R18 RECK RINT1 RSPH14 SF1 SF3A3 SKIL STMN3 SYCE2 SYNE4 TNNT2 TRIM44 TRIM54 TRIM55 TRIM63 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N WASHC1 WWOX ZNF483
Entrez ID		2110	140691
HPRD ID		01978	11518
Ensembl ID		ENSG00000171503	ENSG00000185880
Uniprot IDs		B4DEQ0 Q16134	H0YL66 Q86WT6
PDB IDs			4NQJ 6YXE
Enriched GO Terms of Interacting Partners?
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