TRIM69 and TRIM44

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		TRIM69	TRIM44
Description		tripartite motif containing 69	tripartite motif containing 44
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Nuclear Speck	Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Apoptotic Process Protein Ubiquitination	Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Defense Response To Virus By Host Regulation Of Gene Expression Protein Ubiquitination Positive Regulation Of Transcription, DNA-templated Protein Stabilization Negative Regulation Of Protein K48-linked Ubiquitination Positive Regulation Of NIK/NF-kappaB Signaling
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Estimated glomerular filtration rate in non-diabetics ( 31451708)	Metabolite levels ( 23823483) Photic sneeze reflex ( 27182965) Response to antipsychotic therapy (extrapyramidal side effects) ( 19875103)
Interacting Genes		53 interacting genes: AIFM2 APP ASNS ATP5MC1 BEX2 BIN3 C4orf45 CDSN DVL1 ETFDH FAM110A FAM161A FAM90A1 FKBP1B GEM HAUS1 HGS IYD KLHL38 KRT17 LARP1B LYSMD1 MAGEA4 MAJIN MED20 MID2 NEK8 NTAQ1 PML POLR3K PPP1R18 RECK RINT1 RSPH14 SF1 SF3A3 SKIL STMN3 SYCE2 SYNE4 TNNT2 TRIM44 TRIM54 TRIM55 TRIM63 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N WASHC1 WWOX ZNF483	9 interacting genes: APP FBXO7 HINFP MORN4 NEDD4 PBX3 PICK1 TRIM10 TRIM69
Entrez ID		140691	54765
HPRD ID		11518	15561
Ensembl ID		ENSG00000185880	ENSG00000166326
Uniprot IDs		H0YL66 Q86WT6	Q96DX7
PDB IDs		4NQJ 6YXE
Enriched GO Terms of Interacting Partners?
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