ERBB4 and VAV3

  • Number of citations of the paper that reports this interaction (PubMedID 22973453)
  • 27

ERBB4

VAV3

Description erb-b2 receptor tyrosine kinase 4 vav guanine nucleotide exchange factor 3
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065)
  • Asthma and hay fever ( 24388013)
  • Autoimmune thyroid disease ( 32581359)
  • Bipolar disorder ( 31043756)
  • Differentiated thyroid cancer ( 28703219)
  • Eosinophil percentage of white cells ( 32888494)
  • Facial wrinkles (principal components analysis) ( 33959940)
  • Hashimoto thyroiditis versus Graves' disease ( 25429627)
  • Hip circumference adjusted for BMI ( 28552196)
  • Hypothyroidism ( 30367059 27182965 22493691)
  • IgA nephropathy ( 25305756)
  • Medication use (thyroid preparations) ( 31015401)
  • Night sleep phenotypes ( 27126917)
  • Papillary thyroid cancer ( 28703219)
  • Plasma thyroid-stimulating hormone levels ( 24722205)
  • Refractive error ( 32231278)
  • Response to antiepileptic mood-stabilizing treatment in bipolar disorder ( 32627186)
  • Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
  • Thyroid stimulating hormone levels ( 32769997)
  • Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429)
Interacting Genes 152 interacting genes: ABL1 ABL2 ADAM17 ALDOA ANKS1A ANKS1B BCAR3 BLK BMPR2 BTC CASP10 CASP8 CCN2 CD44 CDC25C CFL1 CRK DLG1 DLG2 DLG3 DLG4 DUSP10 DUSP14 DUSP16 DUSP18 DUSP19 DUSP21 DUSP6 EGFR ERBB2 ERBB3 EREG ERG28 FAM241B FES FGR FKBP1A GABARAPL2 GRAP2 GRB10 GRB2 GRB7 HBEGF HCK HDAC6 HSH2D ILKAP INPPL1 IRF2BP2 ITCH ITK LCK LCP2 LRRC7 LYN MATK MTMR2 MTMR6 MTMR9 MUC1 MUC4 NCK1 NCK2 NEDD4 NRG1 NRG2 NRG3 NRG4 NTRK2 PIK3R1 PIK3R2 PIK3R3 PIN4 PLCG1 PLCG2 PPM1A PPM1B PPM1F PRDX5 PRRG4 PTK6 PTPDC1 PTPN11 PTPN12 PTPN20 PTPN21 PTPN6 PTPN7 PTPRH PTPRR PTPRT RASA1 RNF41 RTN4 S100A11 SELENOK SH2B1 SH2B2 SH2B3 SH2D1A SH2D1B SH2D2A SH2D3C SH3BP2 SHB SHC1 SHC2 SHC3 SHC4 SHD SLA SLA2 SMIM20 SNAP91 SNTB2 SOCS1 SOCS2 SOCS3 SOCS5 SOCS6 SRC STAP1 STAT5A STAT5B STYX SYK SYNM TAB1 TAB2 TEC TFAP2C TGFA TMA7 TMEM134 TMEM14A TMEM230 TNS1 TNS2 TNS3 TNS4 TRO TVP23B TXK TXN VAV1 VAV2 VAV3 WWOX YAP1 YES1 ZAP70 ZNF532 25 interacting genes: AR CBLB EGFR ERBB2 ERBB3 ERBB4 ESR1 GAB1 GRB2 IGF1R INSR KIT LCP2 MET PIK3R1 PLCG1 RAC1 RHOA RHOG RINT1 ROS1 SH3BP2 SHC1 ZRANB1 ZYX
Entrez ID 2066 10451
HPRD ID 02767 05706
Ensembl ID ENSG00000178568 ENSG00000134215
Uniprot IDs Q15303 Q9UKW4
PDB IDs 2AHX 2L2T 2LCX 2R4B 3BBT 3BBW 3BCE 3U2P 3U7U 3U9U 2D86
Enriched GO Terms of Interacting Partners?
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