ELK3 and PIAS1

  • Number of citations of the paper that reports this interaction (PubMedID 15580297)
  • 7
  • Data Source:
  • HPRD (in vivo, in vitro, two hybrid)

ELK3

PIAS1

Description ETS transcription factor ELK3 protein inhibitor of activated STAT 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia in childhood (B cell precursor) ( 29632299 27694927)
  • B-cell acute lymphoblastic leukaemia ( 31767839)
  • Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382)
  • Small intestine neuroendocrine tumor ( 27492634)
  • Thyroid stimulating hormone levels ( 32769997)
  • Vaginal microbiome composition (community state type) ( 32723796)
  • Diastolic blood pressure ( 30224653)
  • Diverticular disease ( 30177863)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Haemorrhoidal disease ( 33888516)
  • Major depressive disorder ( 23377640)
  • Number of twin births ( 30760885)
Interacting Genes 14 interacting genes: APAF1 APP BPIFA1 CRK CTBP1 ID2 MAPK14 MAPK8 MAPK9 PFDN5 PIAS1 SP4 TCF3 TOP1 110 interacting genes: AKT1 AR ATXN1 AXIN1 BARD1 BRCA1 CASP8 CBS CDK4 CEBPA CEBPE CHD3 CHUK CNOT7 CREB1 CREBBP CSNK2A1 CSRP2 DCLRE1A DDX21 DDX5 DNM1 DNMT3A ELK3 EP300 ESR1 ESR2 FANCI FHL3 FLI1 GATA4 GLUL GRM8 GSK3B GTF2IRD1 HECTD2 HIC1 HTT IKZF5 JUN KLF3 L3MBTL2 LSM3 MAML1 MBD1 MDC1 MDM2 MITF MSX1 MX1 MYB NCOR1 NFATC1 NIN NR2F2 NR3C2 NR5A1 PAXIP1 PGR PIAS2 PIAS4 PLAG1 PML PPP1CA PPP1CC PRDM1 PRPF40A PSME3 PTK2 PTPN1 QKI RAD54L2 RBBP6 RELA RPA2 SATB1 SATB2 SERBP1 SGTA SKIL SMAD1 SMAD4 SMAD7 SNAI2 SNIP1 SP3 SPOP SREBF2 STAT1 SUFU SUMO1 SUMO1P1 SUMO2 SUMO3 TBP TERF2 TEX11 TP53 TP73 TRIM27 TRIM5 TRIM55 TRIM63 TSG101 UBE2I UBE2L3 YWHAZ ZBED1 ZNF451 ZNF76
Entrez ID 2004 8554
HPRD ID 02593 16029
Ensembl ID ENSG00000111145 ENSG00000033800
Uniprot IDs A0A024RBE2 P41970 O75925 Q1XBU8
PDB IDs 1V66
Enriched GO Terms of Interacting Partners?
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