CADM4 and CSNK1E

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		CADM4	CSNK1E
Description		cell adhesion molecule 4	casein kinase 1 epsilon
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Cell Leading Edge Cell-cell Contact Zone	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Phosphatase Binding Receptor Tyrosine Kinase Binding Vascular Endothelial Growth Factor Receptor 1 Binding Vascular Endothelial Growth Factor Receptor 2 Binding	RNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Regulation Of Protein Phosphorylation Negative Regulation Of Protein Phosphorylation Cell Adhesion Negative Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Rac Protein Signal Transduction Regulation Of Cell Population Proliferation Negative Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Wound Healing Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Cell Motility	DNA Repair Protein Phosphorylation Endocytosis Signal Transduction Wnt Signaling Pathway Peptidyl-serine Phosphorylation Negative Regulation Of Protein Binding Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Canonical Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cellular Protein Localization Positive Regulation Of Wnt-mediated Midbrain Dopaminergic Neuron Differentiation Positive Regulation Of Non-canonical Wnt Signaling Pathway
Pathways			WNT mediated activation of DVL Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Circadian Clock Anchoring of the basal body to the plasma membrane Major pathway of rRNA processing in the nucleolus and cytosol AURKA Activation by TPX2
Drugs			Seliciclib
Diseases
GWAS			Keratoconus ( 31855235) Mastocytosis ( 32752121)
Interacting Genes		3 interacting genes: CNKSR1 CSNK1E DYNC1I1	55 interacting genes: AKAP9 ANKRD6 APC APP ARHGEF1 ARNTL AXIN1 AXIN2 BBS10 BHLHE41 BID CADM4 CLOCK CRY1 CSNK2B DELEC1 DVL1 DVL2 DVL3 ENTR1 FAM110A FAM110C FAM83D FBP1 FBXO7 FBXW11 GTF3C1 HES1 KAT7 MCC NCOA3 NR1D2 PER1 PER2 PER3 PPP1CA PPP1CC PPP1R14A PPP2R5D PPP2R5E PTPRC PTPRD RAD54B RBX1 RORA RORC SOCS3 TAFAZZIN TAOK1 TNS2 TRIM3 WDCP ZMYND8 ZNF227 ZNF618
Entrez ID		199731	1454
HPRD ID		17141	02919
Ensembl ID		ENSG00000105767	ENSG00000213923
Uniprot IDs		Q8NFZ8	P49674 Q5U045
PDB IDs			4HNI 4HOK
Enriched GO Terms of Interacting Partners?
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