UBR1 and NDUFA4L2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

		UBR1	NDUFA4L2
Description		ubiquitin protein ligase E3 component n-recognin 1	NDUFA4 mitochondrial complex associated like 2
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Proteasome Complex Cytoplasm Cytosol	Mitochondrial Respiratory Chain Complex IV
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity Leucine Binding
	Biological Process	Protein Ubiquitination Negative Regulation Of TOR Signaling Cellular Response To Leucine Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs			NADH
Diseases
GWAS		Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) MGMT methylation in smokers ( 26183928) Triglycerides ( 25961943)	Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 25056061 29483656)
Interacting Genes		31 interacting genes: ANXA3 ARL15 ARL3 ARL4D ATF3 BCL2L1 BTBD2 CDC42 CDC6 DLEU1 DNAJB11 FOS FTH1 GADD45A GSK3B LAMA4 LAMTOR3 NDUFA4L2 NR3C1 NTAN1 NTAQ1 NUDT3 PKNOX1 PTPRS SERPINB9 SPRY2 TAC3 TP53I3 UBE2A UBE2B UBE2D2	14 interacting genes: ANXA9 C6orf62 COMMD8 DYNLL1 EIF3C ERG28 KAT5 KCNA4 LUC7L2 NUFIP2 PRKN QTRT1 SLC35F6 UBR1
Entrez ID		197131	56901
HPRD ID		09342	14249
Ensembl ID		ENSG00000159459	ENSG00000185633
Uniprot IDs		Q8IWV7	A0A024RB39 Q9NRX3
PDB IDs		3NY1 5TDC
Enriched GO Terms of Interacting Partners?
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