PLPP4 and GJB5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLPP4	GJB5
Description		phospholipid phosphatase 4	gap junction protein beta 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Connexin Complex Integral Component Of Membrane
	Molecular Function	Diacylglycerol Diphosphate Phosphatase Activity Protein Binding Phosphatidate Phosphatase Activity Lipid Phosphatase Activity Identical Protein Binding	Gap Junction Channel Activity Protein Binding
	Biological Process	Blastocyst Hatching Phospholipid Metabolic Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Phospholipid Dephosphorylation Regulation Of Calcium Ion Import	Cell-cell Signaling Epidermis Development Transmembrane Transport Trophoblast Giant Cell Differentiation Labyrinthine Layer Morphogenesis Epididymis Development
Pathways		Role of phospholipids in phagocytosis	Gap junction assembly
Drugs
Diseases
GWAS		Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189)	BMI x environmental factors (excluding physical activity) interaction ( 33654129) BMI x environmental factors (including physical activity) interaction ( 33654129) Narcolepsy ( 23459209) Sleep duration (short sleep) ( 30846698) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		33 interacting genes: ANKRD46 ARL13B BCL2L13 BIK BMP10 CD74 CISD2 CPLX4 CREB3L1 CYB5B ERGIC3 EVI2A FAM209A FRMD3 GET1 GJA1 GJB5 GPX8 LMNA LRRC59 MGST3 PAGE1 PDZK1IP1 PSCA SGPL1 SLC35A1 SSMEM1 STX1A STX2 SYT2 TMEM139 TMEM45B UPK1B	45 interacting genes: APOL2 APOL3 AQP1 C1GALT1 C4orf3 COMT CTXN3 CYB5B DNALI1 ERG28 FAM3C GSK3B IGFBP5 JAGN1 LMNA LPAR3 LRP10 MED1 MIP MS4A13 MYL2 NAPB PCGF2 PGAP2 PLPP4 PLPP6 PNLIPRP1 RPRM RTP2 SEC22A SEC22B SERP1 SLC30A2 SLC38A7 SLC41A1 SLC41A2 SMIM1 TM4SF4 TMEM128 TMEM60 TMEM86A TMEM97 TRIM2 TSPO2 VSTM1
Entrez ID		196051	2709
HPRD ID		18745	06840
Ensembl ID		ENSG00000203805	ENSG00000189280
Uniprot IDs		B7Z3R3 Q5VZY2	A0A654IE64 O95377
PDB IDs
Enriched GO Terms of Interacting Partners?
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