APLNR and MTCH1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		APLNR	MTCH1
Description		apelin receptor	mitochondrial carrier 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Mitochondrion Mitochondrial Outer Membrane Membrane Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Signaling Receptor Activity Apelin Receptor Activity	Protein Binding
	Biological Process	Angiogenesis Blood Vessel Development Vasculogenesis Vasculature Development Heart Looping Atrioventricular Valve Development Endocardial Cushion Formation G Protein-coupled Receptor Signaling Pathway Gastrulation Heart Development Adult Heart Development Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Histone Deacetylation Vascular Associated Smooth Muscle Cell Differentiation Aorta Development Negative Regulation Of CAMP-mediated Signaling Positive Regulation Of Angiogenesis Regulation Of Body Fluid Levels Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Apelin Receptor Signaling Pathway Ventricular Septum Morphogenesis Venous Blood Vessel Development Coronary Vasculature Development Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Gap Junction Assembly Positive Regulation Of Inhibitory G Protein-coupled Receptor Phosphorylation	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Signal Transduction Positive Regulation Of Apoptotic Process Neuronal Ion Channel Clustering
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678)
Interacting Genes		8 interacting genes: AKR1B1 APLN GJB2 LAMP2 MARK4 MTCH1 NDRG4 SETD3	10 interacting genes: APLNR ATP2A3 EML4 ERBB2 GSK3A KCNJ15 LGSN NQO2 PSEN1 ZFAND3
Entrez ID		187	23787
HPRD ID		02503	14787
Ensembl ID		ENSG00000134817	ENSG00000137409
Uniprot IDs		B2RDH3 B3KQN4 P35414	A0A024RCX4 A0A024RD08 A8YXX5 B4E0C5 Q9NZJ7
PDB IDs		2LOT 2LOU 2LOV 2LOW 5VBL 6KNM
Enriched GO Terms of Interacting Partners?
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