DSC2 and RO60

		DSC2	RO60
Description		desmocollin 2	Ro60, Y RNA binding protein
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Plasma Membrane Cell-cell Junction Intercalated Disc Integral Component Of Membrane Desmosome Cytoplasmic Vesicle Extracellular Exosome	Nucleoplasm Cytosol Ribonucleoprotein Complex
	Molecular Function	Calcium Ion Binding Protein Binding Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication	RNA Binding U2 SnRNA Binding Metal Ion Binding
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication Regulation Of Heart Rate By Cardiac Conduction Cell-cell Adhesion Regulation Of Ventricular Cardiac Muscle Cell Action Potential	Immune System Development Transcription By RNA Polymerase III Smoothened Signaling Pathway Response To UV Regulation Of Gene Expression Cellular Response To Interferon-alpha Cilium Assembly
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Bronchopulmonary dysplasia ( 23897914) Metabolite levels ( 23823483) Response to immune checkpoint inhibitors in melanoma (immune-related adverse events) ( 33409738)
Interacting Genes		12 interacting genes: CDC6 CELF4 CLK1 DSC3 DSG1 DSG2 FHOD3 ITSN1 JUP PKP2 PKP3 RO60	8 interacting genes: CDC42 DDX6 DSC2 OGT RAB11FIP5 RNY1 RNY3 TRIM21
Entrez ID		1824	6738
HPRD ID		00512	15964
Ensembl ID		ENSG00000134755	ENSG00000116747
Uniprot IDs		A0A3B3ISU0 Q02487	A0A024R983 G5E9R9 P10155
PDB IDs		5ERP 5J5J 7A7D
Enriched GO Terms of Interacting Partners?
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