ATN1 and STXBP4

Number of citations of the paper that reports this interaction (PubMedID 16713569)
337

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATN1	STXBP4
Description		atrophin 1	syntaxin binding protein 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Cell Junction Perinuclear Region Of Cytoplasm	Cytoplasmic Vesicle Phagocytic Vesicle Extracellular Exosome
	Molecular Function	Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding	Protein Binding Syntaxin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Neuron Apoptotic Process	Protein Targeting Cellular Response To DNA Damage Stimulus Insulin Receptor Signaling Pathway Regulation Of Glucose Transmembrane Transport Positive Regulation Of Keratinocyte Proliferation Protein Stabilization Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Cellular Response To Interferon-gamma Positive Regulation Of Cell Cycle G1/S Phase Transition
Pathways		Regulation of PTEN gene transcription
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226) Intrinsic epigenetic age acceleration ( 29374233) Menarche (age at onset) ( 25231870) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Night sleep phenotypes ( 27126917) Plateletcrit ( 32888494) Systolic blood pressure ( 34074324) Zinc levels ( 26025379)
Interacting Genes		125 interacting genes: AGRN ALG13 ARF3 ATRX BAG3 BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CENPJ CHRD CRACR2A CRIP2 CSNK2A1 CTNND2 DGCR6L DMPK DMRT3 DVL1 DVL2 ECM1 EFEMP1 EFEMP2 ETNK2 EWSR1 FBLN1 FBLN2 FBLN5 FXR1 FXR2 GAPDH GCC1 GIGYF1 GRN HGS HINFP HNRNPF HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP12-2 KRTAP15-1 KRTAP19-2 KRTAP19-5 KRTAP4-12 KRTAP6-2 KRTAP9-3 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 OLIG3 P4HA3 PCSK5 PDCD6IP PFKL PIN1 PITX1 PITX2 PLSCR1 PPP1R32 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBM14 RBM4B RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SH3RF1 SHANK3 SIAH1 SIAH2 SLC25A48 SLIT1 SPAG5 SS18L1 SSPOP STXBP4 SYVN1 TEKT3 TEP1 TLE1 TLE5 TNFAIP8 TRIP6 TSC1 USP2 USP54 VIM WDR5 WWP1 WWP2 ZMYND8 ZNF503 ZSWIM8	6 interacting genes: ATN1 DYNLL2 ENKD1 KLHL42 STX4 TRIM54
Entrez ID		1822	252983
HPRD ID		06311	18127
Ensembl ID		ENSG00000111676	ENSG00000166263
Uniprot IDs		P54259 Q86V38	B5MCT9 Q6ZWJ1
PDB IDs			2YSG
Enriched GO Terms of Interacting Partners?
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