STXBP4 and KLHL42

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		STXBP4	KLHL42
Description		syntaxin binding protein 4	kelch like family member 42
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasmic Vesicle Phagocytic Vesicle Extracellular Exosome	Spindle Cytosol Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Syntaxin Binding	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Protein Targeting Cellular Response To DNA Damage Stimulus Insulin Receptor Signaling Pathway Regulation Of Glucose Transmembrane Transport Positive Regulation Of Keratinocyte Proliferation Protein Stabilization Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Cellular Response To Interferon-gamma Positive Regulation Of Cell Cycle G1/S Phase Transition	Protein Polyubiquitination Cell Cycle Regulation Of Microtubule-based Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cell Division
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226) Intrinsic epigenetic age acceleration ( 29374233) Menarche (age at onset) ( 25231870) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Night sleep phenotypes ( 27126917) Plateletcrit ( 32888494) Systolic blood pressure ( 34074324) Zinc levels ( 26025379)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Gut microbiota (functional units) ( 27694959) Height ( 31562340) Osteoarthritis (hip) ( 30664745) Refractive error ( 32231278) Resting heart rate ( 27798624) Type 2 diabetes ( 30054458)
Interacting Genes		6 interacting genes: ATN1 DYNLL2 ENKD1 KLHL42 STX4 TRIM54	35 interacting genes: ADD1 ANKRD33 CALCOCO2 CDCA4 CKMT2 COIL CT55 CUL3 DAZAP2 DDI1 FAM168A INCA1 KRTAP19-4 MYOG OIP5 OSTF1 P4HB PFDN5 POMC RCN3 REL SERTAD1 SERTAD3 SSX2IP STAM2 STXBP4 TRIM23 TRIM54 TTC23 UBE2E3 UBQLN1 UBQLN2 UBQLN4 USHBP1 VPS52
Entrez ID		252983	57542
HPRD ID		18127	17237
Ensembl ID		ENSG00000166263	ENSG00000087448
Uniprot IDs		B5MCT9 Q6ZWJ1	B2RNT7 F5H523 Q9P2K6
PDB IDs		2YSG
Enriched GO Terms of Interacting Partners?
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